profile
Dr. Kalyan Sundar Ghosh
Assistant Professor (Gr-I)Dr. Kalyan Sundar Ghosh is presently working as an Assistant Professor (Grade-I) in the Department of Chemistry, National Institute of Technology Hamirpur, Himachal Pradesh, India. Dr. Ghosh had pursued his doctoral research at Department of Chemistry, IIT Kharagpur (Jan 2004 - Jan 2009) under supervision of Prof. Swagata Dasgupta. Then he had worked as Postdoctoral Associate in University of Maryland, College Park, USA and State University of New York, Albany, USA in a broad area of protein chemistry. He has published 44 research articles in international and indexed journals with repute. Some of his publications had crossed more than hundred citations each. His current research interests broadly include Bioorganic and Biophysical Chemistry with special emphasis on protein aggregation and its inhibition using synthetic and natural molecules. Presently his group is also working on bionanomaterials and their applications.
| Name | : | Dr. Kalyan Sundar Ghosh |
| Designation | : | Assistant Professor (Gr-I) |
| Department | : | Chemistry |
| Qualification | : | Ph.D. |
| Phone | : | 01972-254104 |
| Email ID | : | kalyan@nith.ac.in |
| Google Scholar Link | : | View |
General Information
| Name | : | Dr. Kalyan Sundar Ghosh |
| Designation | : | Assistant Professor (Gr-I) |
| Department | : | Chemistry |
| Qualification | : | Ph.D. |
| Date of Birth | : | 04/29/1982 |
| Date of joining | : | 05/03/2012 |
Contact Details
| Phone | : | 01972-254104 |
| Email ID | : | kalyan@nith.ac.in |
Specialization
Bioorganic and Biophysical Chemistry
Position Held
| Position | Department Name | Institute Name | Time Period |
|---|
Educational Qualification
| Name of the Degree | Year of Passing | Institute/University |
|---|---|---|
| Ph.D | 2009 | IIT Kharagpur |
| M.Sc. | 2003 | University of Calcutta |
| B.Sc. (Hons) in Chemistry | 2001 | Presidency College, University of Calcutta |
Honors & Recognitions Achieved
| Sr.No. | Title | Activity | Given By | Year |
|---|
Research Experience
| Research Interests : | Bioorganic Chemistry, Biophysical Chemistry, Nanomaterials | |
| Brief Research Statement : | 1. Design and development of chemical and biochemical sensors 2. Studies on the interactions between small molecules and biomacromolecules 3. Protein aggregation and its inhibition by using small molecules (synthetic and natural) and specifically designed nanomaterials |
Journal Publications
| Year | Author(s) | Title & Vol. No. | Journal Name | Indexing (SCI) Web of Science/Scopus |
|---|---|---|---|---|
| 2018 | Dolai, B., Bhaumik, A., Pramanik, N., Ghosh, K. S., Atta, A. K. | Naphthaldimine-based simple glucose derivative as a highly selective sensor for colorimetric detection of Cu2+ ion in aqueous media | J. Mol. Struc. | SCI |
| 2018 | Babu, M. S., Reddy, K. S., Ghosh, K. S., Sahoo, B. K., Himasekar, Ch., Mustafa, S. | Design, Synthesis, Single X-Ray Crystal Structure, DFT and Molecular Docking Studies of Novel Clip Type-Pyridyltetrazole Analogues | Asian J. Chem. | Scopus |
| 2018 | Rana, N., Ghosh, K. S., Chand, S., Gathania, A. K. | Investigation of ZnO nanoparticles for their applications in wastewater treatment and antimicrobial activity | Ind. J. Pure Appl. Phys. | SCI |
| 2017 | Sharma, V., Ghosh, K. S. | Inhibition of amyloid fibrillation and destabilization of fibrils of human ?D-crystallin by direct red 80 and orange G | Intl. J. Biol. Macromol. | SCI |
| 2017 | Chauhan, P., Velappan, A. B., Sahoo, B. K., Debnath, J., Ghosh, K. S. | Studies on molecular interactions between Schiff bases and eye lens chaperone human ?A-crystallin | J. Lumin. | SCI |
| 2017 | Chauhan, P., Muralidharan, S. B., Velappan, A. B., Datta, D., Pratihar, S., Debnath, J., Ghosh, K. S. | Inhibition of copper-mediated aggregation of human ?D-crsytallin by Schiff bases | J. Biol. Inorg. Chem. | SCI |
| 2016 | Sivaramakrishnan, V., Ilamathi, M., Ghosh, K. S., Sathish, S., Gowda, T. V., Vishwanath, B. S., Rangappa, K. S., Dhananjaya, B. L. | Virtual analysis of structurally diverse synthetic analogs as inhibitors of snake venom secretory phospholipase A2 | J. Mol. Recognit. | SCI |
| 2015 | Thakur, R., Das, A., Sharma, V., Adhikari, C., Ghosh, K.S., Chakraborty, A. | Interaction of different prototropic species of an anticancer drug Ellipticine with HSA and IgG proteins: multispectroscopic and molecular modeling studies | Phy. Chem. Chem. Phys. | SCI |
| 2015 | Sharma, A., Ghosh, K. S., Singh, B. P., Gathania, A. K. | Spectroscopic investigation of interaction between bovine gamma globulin and gold nanoparticles | Methods Appl. Fluoresc. | SCI |
| 2014 | Sharma, V., Ghosh, K. S. | Involvement of non-polyalanine (polyA) residues in aggregation of polyA proteins: Clue for inhibition of aggregation | Comp. Biol. Chem. | SCI |
| 2013 | Ghosh, K. S. | Inherent aggregation propensity of flanking residues attached to polyglutamines: implication to aggregation inhibition | Prot. Pept. Lett. | SCI |
| 2013 | Roy, A. S., Ghosh, K. S., Dasgupta, S. | An investigation into the altered binding mode of green tea polyphenols with human serum albumin on complexation with copper | J. Biomol. Struct. Dyn. | SCI |
| 2012 | Roy, D., Dutta, S., Maity, S. S., Ghosh, S., Roy, A. S., Ghosh, K. S., Dasgupta, S. | Spectroscopic and docking studies of the binding of two stereoisomeric antioxidant catechins to serum albumins | J. Lumin. | SCI |
| 2011 | Ghosh, K. S., Pande, A., Pande, J. | Binding of gamma crystallin substrate prevents the binding of copper and zinc ions to the molecular chaperone alpha crystallin | Biochemistry | SCI |
| 2010 | Pande, A., Ghosh, K. S., Banerjee, P. R., Pande, J. | Increase in surface hydrophobicity of the cataract-associated, P23T mutant of human gammaD-crystallin is responsible for its dramatically lower, retrograde solubility | Biochemistry | SCI |
| 2010 | Chandra, G., Ghosh, K. S., Dasgupta, S., Roy, A. | Evidence of conformational changes in adsorbed lysozyme molecule on silver colloids | Intl. J. Biol. Macromol. | SCI |
| 2010 | Mukhopadhyay, S., Maity, S. S., Roy, A., Chattopadhyay, D., Ghosh, K. S., Dasgupta, S., Ghosh, S. | Characterization of the structure of the phosphoprotein of chandipura virus, a negative stranded RNA virus probing intratryptophan energy transfer using single and double tryptophan mutants | Biochimie | SCI |
| 2009 | Sahoo, B. K., Ghosh, K. S., Dasgupta, S. | An Investigation of the molecular interactions of diacetylcurcumin with ribonuclease A | Prot. Pept. Lett. | SCI |
| 2009 | Ghosh, K. S., Sen, S., Sahoo, B. K., Dasgupta, S. | A spectroscopic investigation into the interactions of 3´-O-carboxy esters of thymidine with Bovine Serum Albumin | Bioploymers | SCI |
| 2009 | Sahoo, B. K., Ghosh, K. S., Dasgupta, S. | Molecular interactions of isoxazolcurcumin with human serum albumin: spectroscopic and molecular modeling studies | Bioploymers | SCI |
| 2008 | Ghosh, K. S., Debnath, J., Pathak, T., Dasgupta, S. | Using Proton Nuclear Magnetic Resonance to study the mode of Ribonuclease A inhibition by competitive and noncompetitive inhibitors | Bioorg. Med. Chem. Lett. | SCI |
| 2008 | Ghosh, K. S., Sahoo, B.K., Jana, D., Dasgupta, S. | Studies on interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA | J. Inorg. Biochem. | SCI |
| 2008 | Sahoo, B.K., Ghosh, K. S., Dasgupta, S. | Studies on the interaction of diacetylcurcumin with calf thymus DNA | Chem. Phys. | SCI |
| 2008 | Ghosh, K. S., Debnath, J., Dutta, P., Sahoo, B. K., Dasgupta, S. | Exploring the potential of 3´-O-Carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin | Bioorg. Med. Chem. | SCI |
| 2008 | Ghosh, K. S., Sahoo, B. K., Dasgupta, S. | Spectrophotometric studies on the interaction between (-)-epigallocatechin gallate and lysozyme | Chem. Phys. Lett. | SCI |
| 2008 | Sahoo, B. K., Ghosh, K. S., Dasgupta, S. | Investigating the binding of curcumin derivatives to bovine serum albumin | Biophys. Chem. | SCI |
| 2008 | Bera, R., Sahoo, B. K., Ghosh, K. S., Dasgupta S. (2008) | Studies on the interaction of isoxazolcurcumin with calf thymus DNA | Int. J. Biol. Macromol. | SCI |
| 2008 | Maiti, T. K., Ghosh, K. S., Samanta A., Dasgupta S. | The interaction of silibinin with human serum albumin: a spectroscopic investigation | J. Photochem. Photobiol. A | SCI |
| 2007 | Mandal, C., Gayen, S., Basu, A., Ghosh, K. S., Dasgupta, S., Maiti, M., Sen, S. | Prediction based protein engineering of domain I of Cry2A entomocidal toxin of Bacillus thuringiensis resulted enhancement of toxicity against lepidopteran insects | Protein Eng. Des. Sel. | SCI |
| 2007 | Ghosh, K. S., Maiti, T.K., Debnath, J., Dasgupta, S. | Inhibition of ribonuclease A by polyphenols present in green tea | Proteins | SCI |
| 2006 | Ghosh, K. S., Maiti, T.K., Mandal, A., Dasgupta, S. | Copper complexes of (?)-epicatechin gallate and (?)-epigallocatechin gallate act as inhibitors of ribonuclease A | FEBS Lett. | SCI |
| 2006 | Maiti, T. K., Ghosh, K. S., Dasgupta, S. | Interaction of (-)-epigallocatechin-3-gallate with human serum albumin: fluorescence, fourier transform infrared, circular dichroism and docking studies | Proteins | SCI |
| 2006 | Maiti, T. K., Ghosh, K. S., Debnath, J., Dasgupta, S. | Binding of all-trans retinoic acid to human serum albumin: fluorescence, FT-IR and circular dichroism studies | Int. J. Biol. Macromol. | SCI |
| 2004 | Ghosh, K. S., Maiti, T. K., Dasgupta, S. | Green tea polyphenols as inhibitors of ribonuclease A | Biochem. Biophys. Res. Commun. | SCI |
| 2019 | Sharma, V. and Ghosh, K. S. | Inhibition of amyloid fibrillation by small molecules and nanomaterials: strategic development of pharmaceuticals against amyloidosis, Vol. 26, pp. 315 – 323. | Prot. Pept. Lett. | SCI |
| 2019 | Chauhan, P. and Ghosh, K. S. | Inhibition of copper-induced aggregation of human gammaD-crystallin by rutin and studies on its role in molecular level for enhancing the chaperone activity of human ?A-crystallin by using multi-spectroscopic techniques, Vol. 218, pp. 229-236. | Spectrochim. Acta A | SCI |
| 2019 | S. Rana, A. B. Velappan, J. Debnath, K. S. Ghosh | Inhibition of copper-induced aggregation of human gammaD-crystallin by a diimine molecule and investigations on their molecular interactions | J. Biomol. Strcture Dynamics | SCI |
| 2020 | S. Rana and K. S. Ghosh | Protective role of hesperetin against posttranslational oxidation of tryptophan residue of human ?D-crystallin: A molecular level study | Archives of Biochemistry and Biophysics | SCI |
| 2020 | Rana, S., K.S. Ghosh | Explication of human gammaD-crystallin interactions with its aggregation inhibitor Schiff base at molecular level | J. Mol. Struct. | SCI |
| 2020 | Rana, S., K.S. Ghosh | Inhibition of fibrillation of human gammaD-crystallin by a flavonoid morin | J. Biomol. Strcture Dynamics | SCI |
| 2020 | Rana, S., Sarmah, S., Singha Roy, A., Ghosh, K. S. | Elucidation of molecular interactions between human gammaD-crystallin and quercetin, an inhibitor against tryptophan oxidation | J. Biomol. Strcture Dynamics | SCI |
| 2020 | Sharma, V., Sharma, S., Rana, S., Ghosh, K. S. | Inhibition of amyloid fibrillation of human gammaD-crystallin by gold nanoparticles: Studies at molecular level | Spectrochimica Acta A | SCI |
| 2020 | Sharma, A., Ghosh, K. S. | Studies on molecular interactions between bovine beta-lactoglobulin and silver nanoparticles | Prot. Pept. Lett. | SCI |
| 2020 | Velappan, A.B., Datta, D., Ma, R. Rana, S., Ghosh, K.S., Hari, N., Franzblau, S.G., Debnath, J. | 2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate Mycobacterium tuberculosis in replicating and non-replicating forms | Bioorg. Chem. | SCI |
| 2021 | S. Rana, M. Panwar, K. S. Ghosh | Docking studies with multiple molecular targets associated with SARSCoV-2 for drug repurposing | Coronaviruses | -- |
| 2021 | Sharma, S., K.S. Ghosh | Recent advances (2017-20) in the detection of copper ion by using fluorescence sensors working through transfer of photo-induced electron (PET), excited-state intramolecular proton (ESIPT) and Förster resonance energy (FRET) | Spectrochimica Acta A | SCI |
| 2021 | Sharma, S., K.S. Ghosh | Overview on recently reported fluorometric sensors for the detection of copper ion based on internal charge transfer (ICT), paramagnetic effect and aggregation induced emission (AIE) mechanisms | J. Mol. Struct. | SCI |
Conference Publications
| Year | Author(s) | Title | Conference name with place | Indexing (SCI/Web of science/Scopus) |
|---|
Research Projects
| Role | Project Type | Title | Funding Agency | From | To | Amount | Status | Co-Investigator | Sanction Order | Sanction Date |
|---|---|---|---|---|---|---|---|---|---|---|
| PI | Sponsored | Inhibition of fibrillation of beta and gamma-crystallins: an alternate way against cataract | SERB-DST, GoI | 04/07/2013 | 03/07/2016 | 24.0 lakhs | Completed | NIL | SB/FT/LS-277/2012 | 02/05/2013 |
| PI | Sponsored | Development of Multifunctional Bio-nanomaterial Media for Treatment of Water and Wastewater | TEQIP-II, NIT Hamirpur | 20/03/2014 | 31/03/2015 | 15 lakhs | Completed | NIL | NIT/HMR/TEQIP-II/Research & Development-19/2014/550-56 | 20/03/2014 |
Research Supervision
| Programme Name | Scholar Name | Research Topic | Status | Year | Co-Suprivisor(s) |
|---|---|---|---|---|---|
| Ph.D | Priyanka Chauhan | Schiff Bases and Flavonoids as Inhibitors of Human ?D-crystallin Aggregation and their Interactions with Human ?A-crystallin: An Approach to Impede Cataract | Degree Awarded | 2013 | NIL |
| Ph.D | Vandna Sharma | Studies on Fibrillation of Human gammaD-Crystallin and its Inhibition by using Small Molecules and Nanoparticles | Degree Awarded | 2014 | NIL |
| Ph.D | Shiwani Rana | Inhibition of posttranslational modifications and amyloid fibrillation of human gammaD-crystallin | Thesis submitted | 2016 | NIL |
| Ph.D | Anchal Sharma | Inhibition of protein fibrillation using nanomaterails | In progress (State of Art completed) | 2017 | NIL |
| Ph.D | Shivani Sharma | Studies on interactions between biomacromolecules and nanomaterials | In progress (State of Art completed) | 2018 | NIL |
| M.Tech | Sristhi Verma (M.Sc.) | Protein chemistry | Completed | 2019 | NIL |
| M.Tech | Sheetal (M.Sc.) | Protein chemistry | Completed | 2019 | NIL |
| M.Tech | Subham Sharma (M.Sc) | Bionanochemistry | Completed | 2019 | NIL |
| M.Tech | Arvind (M.Sc) | Bionanochemistry | Completed | 2019 | NIL |
| M.Tech | Sakshi (M.Sc.) | Synthesis & development of metal sensors | Completed | 2020 | NIL |
| M.Tech | Neha (M.Sc.) | Synthesis & development of metal sensors | Completed | 2020 | NIL |
Patents
| Title | Reg./Ref.No. | Date of Award/Filling | Awarding Agencies | Status |
|---|
Teaching Experience
| Position Held | Department and Organization | From | To | Total Experience |
|---|---|---|---|---|
| Assistant Professor | Dept. of Chemistry, NIT Hamirpur | 03/05/2012 | 8 yrs 4 months (Till date) | |
| Senior Assistant Professor | School of Chemical and Biotechnology, SASTRA University, Tamil Nadu | 22/11/2011 | 30/04/2012 | 5 months |
Administrative Experience
| Position Held | Department and Organization | From | To |
|---|---|---|---|
| Assistant Warden | Kailash Boys Hostel, NIT Hamirpur | 24/06/2013 | 27/07/2015 |
| Assistant Warden | Kailash Boys Hostel, NIT Hamirpur | 28/07/2017 | 25/03/2019 |
| Warden | Kailash Boys Hostel, NIT Hamirpur | 01/06/2020 | |
| Warden | Neelkanth Boys Hostel, NIT Hamirpur | 08/08/2020 | 08/02/2021 |
| Warden | Satpura Hostel, NIT Hamirpur | 08/08/2020 | 08/02/2021 |
| Warden | Vindhyachal Boys Hostel, NIT Hamirpur | 08/08/2020 | 22/10/2020 |
| Warden | Dhauladhar Boys Hostel, NIT Hamirpur | 08/08/2020 | 22/10/2020 |
| Warden | Satpura Hostel, NIT Hamirpur | 25/03/2021 |
Book/Chapters Written
| Type | Title | Publisher | Author(s) | ISBN/ISSN No. | Year |
|---|---|---|---|---|---|
| Book Chapter | Crystallins and their complexes | Springer | K. S. Ghosh and P. Chauhan | 978-3-030-28151-9 | 2020 |
| Book Chapter | Fluorescent nanomaterials for cellular imaging | IntechOpen | K. S. Ghosh and A. Sharma | 978-1-83968-040-3 | 2020 |
Expert Talks
| Title | Place | Year | Description of Event |
|---|---|---|---|
| Invited Talk | Indira Gandhi National Tribal University, Amarkantak (A Central University) | 2015 | National Workshop cum Seminar on “Frontiers in Ethnomedicinal Research” |
Consultancy
| Title of Consultancy | Client Organization | Faculty Involved | Amount(INR) | Status |
|---|
International and National Exposure
| Sr.No. | Title | Description |
|---|---|---|
| 1 | Postdoctoral Associate | State University of New York, Albany |
| 2 | Postdoctoral Associate | University of Maryland, College Park |
Conferences/Courses Organized
| Category | Type | Title | Venue | From | To | Designation |
|---|---|---|---|---|---|---|
| conference | National | Recent Trends in Chemical Sciences, Engineering and Technology (RTCET 2014) | NIT Hamirpur | 29/05/2014 | 30/05/2014 | Co-Convener |
| stc | GIAN Course | Advanced Nanomaterials: Applications in Disease Diagnosis and Imaging | NIT Hamirpur | 30/05/2016 | 03/06/2016 | Coordinator |
| stc | GIAN Course | Chemical, Biochemical and Environmental Issues Related to Cancer and Solutions Addressing Problems | NIT Hamirpur | 11/09/2017 | 16/09/2017 | Coordinator |
| conference | National | Recent Trends in Chemical Sciences & Engineering (RTCSE - 2017) | NIT Hamirpur | 13/10/2017 | 14/10/2017 | Organizing Secretary |
| workshop | National | Recent Advances in Characterization of Multi-functional Materials | NIT Hamirpur | 17/02/2020 | 22/02/2020 | Convener |
Profile Summary
Last Update: 04/04/2021 08:35pm
| Name | : | Dr. Kalyan Sundar Ghosh |
| Designation | : | Assistant Professor (Gr-I) |
| Department | : | Chemistry |
| Qualification | : | Ph.D. |
| Phone | : | 01972-254104 |
| Email ID | : | kalyan@nith.ac.in |
| Profile URL | : | https://portfolios.nith.ac.in/index.php?/nith/dr-kalyan-sundar-ghosh- |
| Date of Birth | : | 04/29/1982 |
| Date of Joining | : | 05/03/2012 |
Specialization
Bioorganic and Biophysical Chemistry
Education Qualification
| Name of the Degree | Year of Passing | Institute/University |
|---|---|---|
| Ph.D | 2009 | IIT Kharagpur |
| M.Sc. | 2003 | University of Calcutta |
| B.Sc. (Hons) in Chemistry | 2001 | Presidency College, University of Calcutta |
Teaching Experience
| Programme Name | Department And Organization | From | To | Total Experience |
|---|---|---|---|---|
| Assistant Professor | Dept. of Chemistry, NIT Hamirpur | 03/05/2012 | 8 yrs 4 months (Till date) | |
| Senior Assistant Professor | School of Chemical and Biotechnology, SASTRA University, Tamil Nadu | 22/11/2011 | 30/04/2012 | 5 months |
Administrative Experience
| Position Held | Department And Organization | From | To |
|---|---|---|---|
| Assistant Warden | Kailash Boys Hostel, NIT Hamirpur | 24/06/2013 | 27/07/2015 |
| Assistant Warden | Kailash Boys Hostel, NIT Hamirpur | 28/07/2017 | 25/03/2019 |
| Warden | Kailash Boys Hostel, NIT Hamirpur | 01/06/2020 | |
| Warden | Neelkanth Boys Hostel, NIT Hamirpur | 08/08/2020 | 08/02/2021 |
| Warden | Satpura Hostel, NIT Hamirpur | 08/08/2020 | 08/02/2021 |
| Warden | Vindhyachal Boys Hostel, NIT Hamirpur | 08/08/2020 | 22/10/2020 |
| Warden | Dhauladhar Boys Hostel, NIT Hamirpur | 08/08/2020 | 22/10/2020 |
| Warden | Satpura Hostel, NIT Hamirpur | 25/03/2021 |
Research Experience
| Research Interests : | Bioorganic Chemistry, Biophysical Chemistry, Nanomaterials | |
| Brief Research Statement : | 1. Design and development of chemical and biochemical sensors 2. Studies on the interactions between small molecules and biomacromolecules 3. Protein aggregation and its inhibition by using small molecules (synthetic and natural) and specifically designed nanomaterials |
Research Projects
| Role | Project Type | Title | Funding Agency | From | To | Amount | Status | Co-Investigator | Sanction Order | Sanction Date |
|---|---|---|---|---|---|---|---|---|---|---|
| PI | Sponsored | Inhibition of fibrillation of beta and gamma-crystallins: an alternate way against cataract | SERB-DST, GoI | 04/07/2013 | 03/07/2016 | 24.0 lakhs | Completed | NIL | SB/FT/LS-277/2012 | 02/05/2013 |
| PI | Sponsored | Development of Multifunctional Bio-nanomaterial Media for Treatment of Water and Wastewater | TEQIP-II, NIT Hamirpur | 20/03/2014 | 31/03/2015 | 15 lakhs | Completed | NIL | NIT/HMR/TEQIP-II/Research & Development-19/2014/550-56 | 20/03/2014 |
Journal Publications
| Year | Author(s) | Journal Name | Title & Vol. No. | Indexing (SCI/Web of science/Scopus) |
|---|---|---|---|---|
| 2018 | Dolai, B., Bhaumik, A., Pramanik, N., Ghosh, K. S., Atta, A. K. | J. Mol. Struc. | Naphthaldimine-based simple glucose derivative as a highly selective sensor for colorimetric detection of Cu2+ ion in aqueous media | SCI |
| 2018 | Babu, M. S., Reddy, K. S., Ghosh, K. S., Sahoo, B. K., Himasekar, Ch., Mustafa, S. | Asian J. Chem. | Design, Synthesis, Single X-Ray Crystal Structure, DFT and Molecular Docking Studies of Novel Clip Type-Pyridyltetrazole Analogues | Scopus |
| 2018 | Rana, N., Ghosh, K. S., Chand, S., Gathania, A. K. | Ind. J. Pure Appl. Phys. | Investigation of ZnO nanoparticles for their applications in wastewater treatment and antimicrobial activity | SCI |
| 2017 | Sharma, V., Ghosh, K. S. | Intl. J. Biol. Macromol. | Inhibition of amyloid fibrillation and destabilization of fibrils of human ?D-crystallin by direct red 80 and orange G | SCI |
| 2017 | Chauhan, P., Velappan, A. B., Sahoo, B. K., Debnath, J., Ghosh, K. S. | J. Lumin. | Studies on molecular interactions between Schiff bases and eye lens chaperone human ?A-crystallin | SCI |
| 2017 | Chauhan, P., Muralidharan, S. B., Velappan, A. B., Datta, D., Pratihar, S., Debnath, J., Ghosh, K. S. | J. Biol. Inorg. Chem. | Inhibition of copper-mediated aggregation of human ?D-crsytallin by Schiff bases | SCI |
| 2016 | Sivaramakrishnan, V., Ilamathi, M., Ghosh, K. S., Sathish, S., Gowda, T. V., Vishwanath, B. S., Rangappa, K. S., Dhananjaya, B. L. | J. Mol. Recognit. | Virtual analysis of structurally diverse synthetic analogs as inhibitors of snake venom secretory phospholipase A2 | SCI |
| 2015 | Thakur, R., Das, A., Sharma, V., Adhikari, C., Ghosh, K.S., Chakraborty, A. | Phy. Chem. Chem. Phys. | Interaction of different prototropic species of an anticancer drug Ellipticine with HSA and IgG proteins: multispectroscopic and molecular modeling studies | SCI |
| 2015 | Sharma, A., Ghosh, K. S., Singh, B. P., Gathania, A. K. | Methods Appl. Fluoresc. | Spectroscopic investigation of interaction between bovine gamma globulin and gold nanoparticles | SCI |
| 2014 | Sharma, V., Ghosh, K. S. | Comp. Biol. Chem. | Involvement of non-polyalanine (polyA) residues in aggregation of polyA proteins: Clue for inhibition of aggregation | SCI |
| 2013 | Ghosh, K. S. | Prot. Pept. Lett. | Inherent aggregation propensity of flanking residues attached to polyglutamines: implication to aggregation inhibition | SCI |
| 2013 | Roy, A. S., Ghosh, K. S., Dasgupta, S. | J. Biomol. Struct. Dyn. | An investigation into the altered binding mode of green tea polyphenols with human serum albumin on complexation with copper | SCI |
| 2012 | Roy, D., Dutta, S., Maity, S. S., Ghosh, S., Roy, A. S., Ghosh, K. S., Dasgupta, S. | J. Lumin. | Spectroscopic and docking studies of the binding of two stereoisomeric antioxidant catechins to serum albumins | SCI |
| 2011 | Ghosh, K. S., Pande, A., Pande, J. | Biochemistry | Binding of gamma crystallin substrate prevents the binding of copper and zinc ions to the molecular chaperone alpha crystallin | SCI |
| 2010 | Pande, A., Ghosh, K. S., Banerjee, P. R., Pande, J. | Biochemistry | Increase in surface hydrophobicity of the cataract-associated, P23T mutant of human gammaD-crystallin is responsible for its dramatically lower, retrograde solubility | SCI |
| 2010 | Chandra, G., Ghosh, K. S., Dasgupta, S., Roy, A. | Intl. J. Biol. Macromol. | Evidence of conformational changes in adsorbed lysozyme molecule on silver colloids | SCI |
| 2010 | Mukhopadhyay, S., Maity, S. S., Roy, A., Chattopadhyay, D., Ghosh, K. S., Dasgupta, S., Ghosh, S. | Biochimie | Characterization of the structure of the phosphoprotein of chandipura virus, a negative stranded RNA virus probing intratryptophan energy transfer using single and double tryptophan mutants | SCI |
| 2009 | Sahoo, B. K., Ghosh, K. S., Dasgupta, S. | Prot. Pept. Lett. | An Investigation of the molecular interactions of diacetylcurcumin with ribonuclease A | SCI |
| 2009 | Ghosh, K. S., Sen, S., Sahoo, B. K., Dasgupta, S. | Bioploymers | A spectroscopic investigation into the interactions of 3´-O-carboxy esters of thymidine with Bovine Serum Albumin | SCI |
| 2009 | Sahoo, B. K., Ghosh, K. S., Dasgupta, S. | Bioploymers | Molecular interactions of isoxazolcurcumin with human serum albumin: spectroscopic and molecular modeling studies | SCI |
| 2008 | Ghosh, K. S., Debnath, J., Pathak, T., Dasgupta, S. | Bioorg. Med. Chem. Lett. | Using Proton Nuclear Magnetic Resonance to study the mode of Ribonuclease A inhibition by competitive and noncompetitive inhibitors | SCI |
| 2008 | Ghosh, K. S., Sahoo, B.K., Jana, D., Dasgupta, S. | J. Inorg. Biochem. | Studies on interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA | SCI |
| 2008 | Sahoo, B.K., Ghosh, K. S., Dasgupta, S. | Chem. Phys. | Studies on the interaction of diacetylcurcumin with calf thymus DNA | SCI |
| 2008 | Ghosh, K. S., Debnath, J., Dutta, P., Sahoo, B. K., Dasgupta, S. | Bioorg. Med. Chem. | Exploring the potential of 3´-O-Carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin | SCI |
| 2008 | Ghosh, K. S., Sahoo, B. K., Dasgupta, S. | Chem. Phys. Lett. | Spectrophotometric studies on the interaction between (-)-epigallocatechin gallate and lysozyme | SCI |
| 2008 | Sahoo, B. K., Ghosh, K. S., Dasgupta, S. | Biophys. Chem. | Investigating the binding of curcumin derivatives to bovine serum albumin | SCI |
| 2008 | Bera, R., Sahoo, B. K., Ghosh, K. S., Dasgupta S. (2008) | Int. J. Biol. Macromol. | Studies on the interaction of isoxazolcurcumin with calf thymus DNA | SCI |
| 2008 | Maiti, T. K., Ghosh, K. S., Samanta A., Dasgupta S. | J. Photochem. Photobiol. A | The interaction of silibinin with human serum albumin: a spectroscopic investigation | SCI |
| 2007 | Mandal, C., Gayen, S., Basu, A., Ghosh, K. S., Dasgupta, S., Maiti, M., Sen, S. | Protein Eng. Des. Sel. | Prediction based protein engineering of domain I of Cry2A entomocidal toxin of Bacillus thuringiensis resulted enhancement of toxicity against lepidopteran insects | SCI |
| 2007 | Ghosh, K. S., Maiti, T.K., Debnath, J., Dasgupta, S. | Proteins | Inhibition of ribonuclease A by polyphenols present in green tea | SCI |
| 2006 | Ghosh, K. S., Maiti, T.K., Mandal, A., Dasgupta, S. | FEBS Lett. | Copper complexes of (?)-epicatechin gallate and (?)-epigallocatechin gallate act as inhibitors of ribonuclease A | SCI |
| 2006 | Maiti, T. K., Ghosh, K. S., Dasgupta, S. | Proteins | Interaction of (-)-epigallocatechin-3-gallate with human serum albumin: fluorescence, fourier transform infrared, circular dichroism and docking studies | SCI |
| 2006 | Maiti, T. K., Ghosh, K. S., Debnath, J., Dasgupta, S. | Int. J. Biol. Macromol. | Binding of all-trans retinoic acid to human serum albumin: fluorescence, FT-IR and circular dichroism studies | SCI |
| 2004 | Ghosh, K. S., Maiti, T. K., Dasgupta, S. | Biochem. Biophys. Res. Commun. | Green tea polyphenols as inhibitors of ribonuclease A | SCI |
| 2019 | Sharma, V. and Ghosh, K. S. | Prot. Pept. Lett. | Inhibition of amyloid fibrillation by small molecules and nanomaterials: strategic development of pharmaceuticals against amyloidosis, Vol. 26, pp. 315 – 323. | SCI |
| 2019 | Chauhan, P. and Ghosh, K. S. | Spectrochim. Acta A | Inhibition of copper-induced aggregation of human gammaD-crystallin by rutin and studies on its role in molecular level for enhancing the chaperone activity of human ?A-crystallin by using multi-spectroscopic techniques, Vol. 218, pp. 229-236. | SCI |
| 2019 | S. Rana, A. B. Velappan, J. Debnath, K. S. Ghosh | J. Biomol. Strcture Dynamics | Inhibition of copper-induced aggregation of human gammaD-crystallin by a diimine molecule and investigations on their molecular interactions | SCI |
| 2020 | S. Rana and K. S. Ghosh | Archives of Biochemistry and Biophysics | Protective role of hesperetin against posttranslational oxidation of tryptophan residue of human ?D-crystallin: A molecular level study | SCI |
| 2020 | Rana, S., K.S. Ghosh | J. Mol. Struct. | Explication of human gammaD-crystallin interactions with its aggregation inhibitor Schiff base at molecular level | SCI |
| 2020 | Rana, S., K.S. Ghosh | J. Biomol. Strcture Dynamics | Inhibition of fibrillation of human gammaD-crystallin by a flavonoid morin | SCI |
| 2020 | Rana, S., Sarmah, S., Singha Roy, A., Ghosh, K. S. | J. Biomol. Strcture Dynamics | Elucidation of molecular interactions between human gammaD-crystallin and quercetin, an inhibitor against tryptophan oxidation | SCI |
| 2020 | Sharma, V., Sharma, S., Rana, S., Ghosh, K. S. | Spectrochimica Acta A | Inhibition of amyloid fibrillation of human gammaD-crystallin by gold nanoparticles: Studies at molecular level | SCI |
| 2020 | Sharma, A., Ghosh, K. S. | Prot. Pept. Lett. | Studies on molecular interactions between bovine beta-lactoglobulin and silver nanoparticles | SCI |
| 2020 | Velappan, A.B., Datta, D., Ma, R. Rana, S., Ghosh, K.S., Hari, N., Franzblau, S.G., Debnath, J. | Bioorg. Chem. | 2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate Mycobacterium tuberculosis in replicating and non-replicating forms | SCI |
| 2021 | S. Rana, M. Panwar, K. S. Ghosh | Coronaviruses | Docking studies with multiple molecular targets associated with SARSCoV-2 for drug repurposing | -- |
| 2021 | Sharma, S., K.S. Ghosh | Spectrochimica Acta A | Recent advances (2017-20) in the detection of copper ion by using fluorescence sensors working through transfer of photo-induced electron (PET), excited-state intramolecular proton (ESIPT) and Förster resonance energy (FRET) | SCI |
| 2021 | Sharma, S., K.S. Ghosh | J. Mol. Struct. | Overview on recently reported fluorometric sensors for the detection of copper ion based on internal charge transfer (ICT), paramagnetic effect and aggregation induced emission (AIE) mechanisms | SCI |
Conference Publications
| Year | Author(s) | Conference | Title | Indexing |
|---|
Book/Chapters Written
| Type (Book/Chapter) | Author(s) | Title | Publisher | ISBN/ISSN No. | Year |
|---|---|---|---|---|---|
| Book Chapter | K. S. Ghosh and P. Chauhan | Crystallins and their complexes | Springer | 978-3-030-28151-9 | 2020 |
| Book Chapter | K. S. Ghosh and A. Sharma | Fluorescent nanomaterials for cellular imaging | IntechOpen | 978-1-83968-040-3 | 2020 |
Research Supersion
| Programme Name | Scholar Name | Research Topic | Status | Year | Co-Superivisor(s) |
|---|---|---|---|---|---|
| Ph.D | Priyanka Chauhan | Schiff Bases and Flavonoids as Inhibitors of Human ?D-crystallin Aggregation and their Interactions with Human ?A-crystallin: An Approach to Impede Cataract | Degree Awarded | 2013 | NIL |
| Ph.D | Vandna Sharma | Studies on Fibrillation of Human gammaD-Crystallin and its Inhibition by using Small Molecules and Nanoparticles | Degree Awarded | 2014 | NIL |
| Ph.D | Shiwani Rana | Inhibition of posttranslational modifications and amyloid fibrillation of human gammaD-crystallin | Thesis submitted | 2016 | NIL |
| Ph.D | Anchal Sharma | Inhibition of protein fibrillation using nanomaterails | In progress (State of Art completed) | 2017 | NIL |
| Ph.D | Shivani Sharma | Studies on interactions between biomacromolecules and nanomaterials | In progress (State of Art completed) | 2018 | NIL |
| M.Tech | Sristhi Verma (M.Sc.) | Protein chemistry | Completed | 2019 | NIL |
| M.Tech | Sheetal (M.Sc.) | Protein chemistry | Completed | 2019 | NIL |
| M.Tech | Subham Sharma (M.Sc) | Bionanochemistry | Completed | 2019 | NIL |
| M.Tech | Arvind (M.Sc) | Bionanochemistry | Completed | 2019 | NIL |
| M.Tech | Sakshi (M.Sc.) | Synthesis & development of metal sensors | Completed | 2020 | NIL |
| M.Tech | Neha (M.Sc.) | Synthesis & development of metal sensors | Completed | 2020 | NIL |
Patents
| Name | Reg./Ref.No. | Date of Award/Filling | Awarding Agencies | Status |
|---|
Conferences/Workshop/Courses Organized
| Category | Type | Title | Venue | From | To | Designation |
|---|---|---|---|---|---|---|
| conference | National | Recent Trends in Chemical Sciences, Engineering and Technology (RTCET 2014) | NIT Hamirpur | 29/05/2014 | 30/05/2014 | Co-Convener |
| stc | GIAN Course | Advanced Nanomaterials: Applications in Disease Diagnosis and Imaging | NIT Hamirpur | 30/05/2016 | 03/06/2016 | Coordinator |
| stc | GIAN Course | Chemical, Biochemical and Environmental Issues Related to Cancer and Solutions Addressing Problems | NIT Hamirpur | 11/09/2017 | 16/09/2017 | Coordinator |
| conference | National | Recent Trends in Chemical Sciences & Engineering (RTCSE - 2017) | NIT Hamirpur | 13/10/2017 | 14/10/2017 | Organizing Secretary |
| workshop | National | Recent Advances in Characterization of Multi-functional Materials | NIT Hamirpur | 17/02/2020 | 22/02/2020 | Convener |
Expert Talks
| Title | Place | Year | Description of Event |
|---|---|---|---|
| Invited Talk | Indira Gandhi National Tribal University, Amarkantak (A Central University) | 2015 | National Workshop cum Seminar on “Frontiers in Ethnomedicinal Research” |
Consultancy
| Title of Consultancy | Client Organization | Faculty Involved | Amount(INR) | Status |
|---|
International and National Exposure
| Sr.No. | Title | Description |
|---|---|---|
| 1 | Postdoctoral Associate | State University of New York, Albany |
| 2 | Postdoctoral Associate | University of Maryland, College Park |
Honors & Recognitions Achieved
| Sr.No. | Title | Activity | Given By | Year |
|---|