profile
Dr. Pamita Awasthi
Associate ProfessorResearch interests/Areas- • Synthesis and Biological evaluation of analogues of mitoxantrone – As a potential Anticancer Agents • Interaction of mitoxantrone and its synthesised analogues with DNA sequences using 2D NMR, UV-Visible spectroscopy, Fluorescence spectroscopy, Cyclic voltametery, Viscosity and Molecular Modeling tools in order to design and develop new class of anticancer drugs. • Synthesis, Structural Study (using 1D NMR, FT-IR, Mass etc. spectroscopic tools), Biological study and field evaluation of Juvenile Hormone Analogues (Insect Growth Regulators) containing diverse structural features as a potential environment friendly green pesticides. • Computer Aided Molecule Design using DISCOVERY STUDIO (DST-SERB young scientist project), AUTO DOCK, GAUSSIAN, AMBER .18 (gifted by Dr. Davis Case Rutgers University) etc.
General Information
| Name | : | Dr. Pamita Awasthi |
| Designation | : | Associate Professor |
| Department | : | Chemistry |
| Qualification | : | Ph.D |
| Date of Birth | : | 10/03/1972 |
| Date of joining | : | 27/07/2007 |
Contact Details
| Phone | : | 254140 |
| Email ID | : | pamita@nith.ac.in |
Specialization
Position Held
| Position | Department Name | Institute Name | Time Period |
|---|
Educational Qualification
| Name of the Degree | Year of Passing | Institute/University |
|---|---|---|
| Ph.D | 2000 | Chemistry Department, Himachal Pradesh University, Shimla |
| M.Sc | 1994 | Chemistry Department, Himachal Pradesh University, Shimla |
| B.Sc (Hons.) | 1992 | St. Bede's Collage Shimla |
| Post Doctoral | 2003 | Department of Biotechnology, IIT- Roorkee |
Honors & Recognitions Achieved
| Sr.No. | Title | Activity | Given By | Year |
|---|---|---|---|---|
| 1 | Merit fellowship | Fifth position in Merit B.Sc(Hons.) | H.P. University | 1992 |
| 2 | Post-Doctoral fellowship | Research associate | CSIR-HRD | 2006 |
Research Experience
| Research Interests : | 1. Synthesis of natural product mimics (Juvenile hormone analogues- A sesquiterpieoide class of compounds; 9,10 anthraquinone class of anticancer candidates) 2. Bioassay and biophysical studies on ligand- receptor interaction. 3. Semiemperical and quantum chemical studies on small molecules using computation chemistry tools. 4. 2D -NMR structural configuration of small molecules | |
| Brief Research Statement : |
Journal Publications
| Year | Author(s) | Title & Vol. No. | Journal Name | Indexing (SCI) Web of Science/Scopus |
|---|---|---|---|---|
| 2022 | Anjali Sharma, Pamita Awasthi | Synthesis, cytotoxic evaluation and ct-DNA binding of series of 1, 4-disubstituted anthraquinone-sulfonamide conjugates | Journal of Chemical Sciences | - |
| 2022 | Kirna Devi, Pamita Awasthi | Isoleucine with secondary sulfonamide functionality as anticancer, antibacterial and antifungal agents | Journal of Biomolecular Structure and Dynamics | - |
| 2022 | Harsh Kumar, Jasmeet Kaur, Pamita Awasthi | Investigation of aggregation and surface active properties of cationic Gemini surfactants in the presence of antidepressant drug | Colloids and Surfaces A: Physicochemical and Engineering Aspects | - |
| 2022 | Vandna Devi, Neetika Kumari, Pamita Awasthi | Synthesis, characterization and insect growth regulating study of beta-alanine substituted sulfonamide derivatives as juvenile hormone mimics | Phosphorus, Sulfur, and Silicon and the Related Elements | - |
| 2022 | Vandna Devi, Pamita Awasthi | Synthesis, structural, DFT and bio-assay of novel ethyl 3-(2-(4-chlorophenoxy) acetamido) propanoate on Galleria mellonela (wax moth)–a juvenile hormone mimic as potential | Journal of Molecular Structure | - |
| 2021 | Vandna Devi, Pamita Awasthi | Juvenile hormone mimics with phenyl ether and amide functionality to be insect growth regulators (IGRs): synthesis, characterization, computational and biological study | Journal of Biomolecular Structure and Dynamics | - |
| 2021 | Harsh Kumar, Jasmeet Kaur, Pamita Awasthi | Scrutinizing the Micellization Behaviour of 14-2-14 Gemini Surfactant and Tetradecyltrimethylammonium Bromide in Aqueous Solutions of Betaine Hydrochloride | Journal of Molecular Liquids | - |
| 2021 | Sharma, Pamita Awasthi | Synthesis, characterization, in vivo, molecular docking, ADMET and HOMO-LUMO study of Juvenile hormone analogues having sulfonamide feature as an insect growth regulators. | Journal of Molecular Structure | - |
| 2021 | Pamita Awasthi, Anjali Sharma, Manu Vatsal | Spectroscopic, viscometric and computational binding study of 1 and 2 substituted anthraquinone analogs to be potential anti-cancer agents. | Journal of Molecular Structure | - |
| 2020 | Kirna Devi, Pamita Awasthi | Sulfonamide phenylalanine (SPA) series of analogues as an antibacterial, antifungal, anticancer agents along with p53 tumor suppressor-DNA complex inhibitor–part | Journal of Biomolecular Structure and Dynamics | - |
| 2020 | Manpreet Singh, Pamita Awasthi, Virender Singh | Iodine Catalysed Synthesis of Luminescent β‐Carboline Tethered Thiazolo[4,5‐c]carbazole and Naphtho[2,1‐d]thiazole Derivatives and Estimation of their Light | European Journal of Organic Chemistry | - |
| 2019 | Pamita Awasthi, Manu Vatsal, Anjali Sharma | Structural and biological study of synthesized anthraquinone series of compounds with sulfonamide feature. | Journal of Biomolecular Structure and Dynamics | - |
| 2019 | Pamita Awasthi, Kirna Devi | Structural characterization, photoluminescence, computational studies and bioassay of newly synthesized N-(3-oxo-3-morpholino-1-phenyl-propyl) benzo sulfonamide with | Research on Chemical Intermediates | - |
| 2018 | Nitesh Kumar, Raj Kaushal, Ashun Chaudhary, Saroj Arora, Pamita Awasthi | Titanium based mixed ligand complexes: Synthesis, spectroscopic and in vitro antiproliferative studies. | Inorganic and Nano-Metal Chemistry | - |
| 2018 | Manu Vatsal, Vandna Devi, Pamita Awasthi | Structural and theoretical study of 1-[1-oxo-3-phenyl-(2-benzosulfonamide)-propyl amido]–anthracene-9, 10-dione to be i-motif inhibitor. | Journal of Molecular Structure | - |
| 2018 | Raj Kaushal, Nitesh Kumar, Archana Thakur, Kiran Nehra, Pamita Awasthi, Rajeev Kaushal, Saroj Arora | Synthesis, spectral characterization, antibacterial and anticancer activity of some titanium complexes. | Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents) | - |
| 2016 | Priyanka Sharma, Sunil Thakur, Pamita Awasthi | In silico and bio assay of juvenile hormone analogs as an insect growth regulator against Galleria mellonella (wax moth) – Part I. | Journal of Biomolecular Structure and Dynamics | - |
| 2015 | Pamita Awasthi, Nitesh Kumar, Raj Kaushal, Mohan Kumar, Shrikant Kukreti | Comparative In Vitro Binding Studies of TiCl2 (dpme) 2, Ti (ada) 2 (bzac) 2, and TiCl2 (bzac)(bpme) Titanium Complexes with Calf-Thymus DNA. | Biochemistry research international | - |
| 2015 | Priyanka Sharma, Sunil Thakur, Pamita Awasthi | Synthesis, characterization, biological evaluation and docking study of heterocyclic-based synthetic sulfonamides as potential pesticide against G. mellonella. | Applied biochemistry and biotechnology | - |
| 2015 | Pamita Awasthi, Nitesh Kumar, Raj Kaushal, Mohan Kumar, Shrikant Kukreti | Comparative in vitro binding studies of Ti [Cl. sub. 2][(dpme). sub. 2], Ti [(ada). sub. 2][(bzac). sub. 2], and Ti [Cl. sub. 2](bzac)(bpme) titanium complexes with calf-thymus DNA. | Biochemistry Research International | - |
| 2014 | Nitesh Kumar, Raj Kaushal, Ashun Chaudhary, Saroj Arora, Pamita Awasthi | Synthesis, structural elucidation, and in vitro antiproliferative activities of mixed-ligand titanium complexes. | Medicinal Chemistry Research | - |
| 2014 | Shilpa Dogra, Pamita Awasthi, Sweta Tripathi, TP Pradeep, Maya S Nair, Ritu Barthwal | NMR-based structure of anticancer drug mitoxantrone stacked with terminal base pair of DNA hexamer sequence d-(ATCGAT)2 | Journal of Biomolecular Structure and Dynamics | - |
| 2014 | Raj Kaushal, Nitesh Kumar, Ashun Chaudhary, Saroj Arora, Pamita Awasthi | Research Article Synthesis, Spectral Characterization, and Antiproliferative Studies of Mixed Ligand Titanium Complexes of Adamantylamine. | Bioinorganic Chemistry and Applications | - |
| 2013 | Pamita Awasthi, Shilpa Dogra, Ritu Barthwal | Multispectroscopic methods reveal different modes of interaction of anti cancer drug mitoxantrone with Poly (dG-dC). Poly (dG-dC) and Poly (dA-dT). Poly (dA-dT). | Journal of Photochemistry and Photobiology B: Biology | - |
| 2013 | Shilpa Dogra, Pamita Awasthi, Maya Nair, Ritu Barthwal | Interaction of anticancer drug mitoxantrone with DNA hexamer sequence d-(CTCGAG) 2 by absorption, fluorescence and circular dichroism spectroscopy. | Journal of Photochemistry and Photobiology B: Biology | - |
| 2013 | A Pamita, S Priyanka | Designing and binding mode prediction of juvenile hormone analogues as potential inhibitor for Galleria mellonella. | Journal of Computer Science and Systems Biology | - |
| 2013 | Raj Kaushal, Nitesh Kumar, Pamita Awasthi, Kiran Nehra | Syntheses, characterization, and antibacterial study of titanium complexes. | Turkish Journal of Chemistry | - |
| 2013 | Shilpa Dogra, Pamita Awasthi, Barthwal Ritu | Comparative Molecular Modeling Study of Binding of Mitoxantrone with d-(ATCGAT) 2 and d-(CTCGAG) 2 Hexamer DNA Sequences | nternational Journal of Current Research and Review | - |
| 2013 | Pamita Awasthi, Shilpa Dogra, Lalit K Awasthi, Ritu Barthwal | Interaction of Mitoxantrone and its Analogs with Methylated and Non-methylated CpG Islands in Tetrameric DNA Sequences: A Molecular Modeling Study . | International Journal of Drug Design and Discovery | - |
| 2012 | P Awasthi, P Sharma | In silico screening of the juvabione category of juvenile hormone analogues with juvenile hormone binding protein of Galleria mellonella – a docking study. | Taylor & Francis Group : SAR and QSAR in Environmental Research | - |
| 2011 | R Kaushal, N Kumar, R Kaushal, P Awasthi | An insight into metal based anti-cancer drugs. | Int J Curr Res Rev | - |
| 2008 | Pamita Awasthi, RK Mahajan | Synthesis of some sulphonamide insect juvenile hormone - Part I | Synthesis of some sulphonamide insect juvenile hormone-Part I | - |
| 2006 | Ritu Barthwal, Uma Sharma, Nandana Srivastava, Monica Jain, Pamita Awasthi, Manpreet Kaur, Sudhir Kumar Barthwal, Girjesh Govil | Structure of daunomycin complexed to d-TGATCA by two-dimensional nuclear magnetic resonance spectroscopy | European journal of medicinal chemistry | - |
| 2004 | Ritu Barthwal, Pamita Awasthi, Manpreet Kaur, Uma Sharma, Nandana Srivastava, SK Barthwal, Girjesh Govil | Structure of DNA sequence d-TGATCA by two-dimensional nuclear magnetic resonance spectroscopy and restrained molecular dynamics. | Journal of structural biology | - |
| 2003 | Ritu Barthwal, Monica, Pamita Awasthi, Nandana Srivastava, Uma Sharma, Manpreet Kaur, Girjesh Govil | Structure of DNA hexamer sequence d-CGATCG by two-dimensional nuclear magnetic resonance spectroscopy and restrained molecular dynamics | Journal of Biomolecular Structure and Dynamics | - |
| 2002 | Ved Parkash Patial and Pamita Sharma R.K.Mahajan | Juvenile Hormone like substances: Part XV-Synthesis and biological activities of some juvenile hormone analogues containing sulphonamide feature. | CSIR-NISCAIR : Indian Journal of Chemistry | - |
Conference Publications
| Year | Author(s) | Title | Conference name with place | Indexing (SCI/Web of science/Scopus) |
|---|---|---|---|---|
| 2021 | Neetika Kumari, Vandna Devi, Pamita Awasthi | Quantum Chemical and Molecular Docking Study of commercially used Insect Growth Regulators | 27 th International Conference of International Academy of Physical Sciences (CONIAPS XXVIII) On "Recent Advances in Catalysis Science & Engineering (RACSE)" | - |
| 2021 | Anjali Sharma, Pamita Awasthi | Comparative computational docking study of Mitoxantrone and 2-[1-oxo- 3-phenyl-2-(benzosulfonamide)-propylamido]-anthracene-9,10-dione (B1) with parallel G- Quaderuplex DNA (d-(TTGGGGT)4) fragment of telomeric junction | 27 th International Conference of International Academy of Physical Sciences (CONIAPS XXVIII) On "Recent Advances in Catalysis Science & Engineering (RACSE)" | - |
| 2018 | Anjali Sharma, Manu Vatsal, Ankush Thakur, Aditya Goyal, Kamlesh Kumar, Monika Guleria, Rakesh Ranjan, Sachin Tiwari, Pamita Awasthi | Interaction study of 9(10H)-acridanone with ct-DNA using UV-Visible, Fluorescence & Viscometric techniques | 71th Annual Session of Indian Institute of Chemical Engineers Seamless Chemical Engineering in service of Humanity: Innovations, Opportunities & Challenges (CHEMCON–2018), Department of Chemical Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar. | - |
| 2018 | Manu Vatsal, Anjali Sharma, Vikas Kumar, Sushil kumar, Dilip Garg, Rahul Yadav, Udit Khandara, Rajesh Kumar, Pamita Awasthi | Atomic interaction pattern of anthraquinone with polyAT.polyAT sequence | BICON-2018, Biyani Girls College, Jaipur. | - |
| 2018 | Vandna Devi, Pamita Awasthi | Structural and theoretical study of N-[3-oxoanilino-propyl]benzene sulfonamide to be insect growth regulators : A quantum chemical approach | 71th Annual Session of Indian Institute of Chemical Engineers Seamless Chemical Engineering in Service of Humanity: Innovations, Opportunities & Challenges (CHEMCON-2018) | - |
| 2018 | Raj Kaushal, Nitesh Kumar, Kiran Nehra, Pamita Awasthi*. | Synthesis, Characterization and Antibacterial Study of Titanium(IV) Complexes. | National Symposium on Biotechnology: Present Status and Future Prospectus. March 15-16, 2013. Deenbandhu Chotu Ram University of Science and Technology Murthal, Sonepat-131039. (copy not enclosed) Best oral presentation award | - |
| 2018 | Nitesh Kumar1, Raj Kaushal1, Saroj 2 Arora, shrikant kukreti 3 Pamita Awasthi | Synthesis, Characterization, Cytotoxic and DNA binding studies of titanium complexes | Recent development in chemical sciences and technology: Yound scientist meet. NIT-Rourkela | - |
| 2017 | Kirna Devi and Pamita Awasthi* | Synthesis, Spectral and Docking studies of New Sulfonamide Compounds | Recent Trends in Chemical Sciences And Engineering 13-14 Oct. 2017 at NIT- Hamirpur (H.P) | - |
| 2017 | Pamita Awasthi* and Vandana Devi | Thermodynamic, Docking study and Structural Analysis of N-(6methyl-2-oxo-3-oxa-heptanyl) Benzene Sulfonamide and Juvenile Hormone as Insect growth regulators | Recent Trends in Chemical Sciences And Engineering 13-14 Oct. 2017 NIT- Hamirpur (H.P) | - |
| 2017 | Manu Vatsal, Anjali Sharma, S.S.Kanwar, Ritu Kapoor, Pamita Awasthi* | MIC for determination of Antibacterial behavior of suffonamide derivatives: A quantum Chemical Approach | Recent Trends inChemical Sciences And Engineering 13-14 Oct. 2017 NIT- Hamirpur (H.P) | - |
| 2017 | Kirna Devi and Pamita Awasthi* | Synthesis, Characterization, molecular simulation, antibacterial and antiofungal activities of new sulfonamide compounds | National conference on role of biophysics in academia and industry, Punjab University | - |
| 2017 | PamitaAwasthi*, Vandna, Manu Vatsal, Kirna Devi | Thermodynamic and structural study of n-(1-isopropyl-2-oxo-3-aza-butanyl)benz ene sulfonamide and1-[1-oxo-3-phenyl-2-(p-tosylamide)-propylamido] anthracene9, 10 dione. | Recent trends in plant and environmental science | - |
| 2017 | Manu vatsal; Pamita Awasthi | Molecular modeling of 1{1-oxo-3(3-methyl-2)p-tosylamide)-butyl amido]-anthracene 9,10-dione with d(TCCCCC) to be i-motif inhibitor | NanoSciTech2017, 8-10 Nov. 2017 PU, Chandigarh | - |
| 2017 | Priyanka Sharma and Pamita Awasthi | Comparative Molecular Modelling of Various Non-terpenoids JHAs against Insect pests. | National Conference on Advances in Basic & Applied Sciences at Career Point University, Hamirpur (H.P.) | - |
| 2016 | Pamita Awasthi*, Manu Vatsal | Molecular docking study of1-[1-oxo-3-phenyl-(-2-benzosulfonamide-)-propyl amido] - anthracene-9, 10-dione with ds-DNA to be a potential anticancer agent in Improving Quality of life using nanotechnology | International conference on Improving Quality of life using nanotechnology: Potential role of polymers at Panjab University | - |
| 2016 | Pamita Awasthi* & Priyanka Sharma | “Docking Study of Synthesized Juvenile Hormone Analogues as an Insect Growth 27Regulators” Growth Regulators” | 14th International Conference on Modelling and Simulation, (UKSim) - 2012. Cambridge University | - |
| 2016 | Priyanka Sharma, Pamita Awasthi | Comparative Insect Growth Regulators Effect of two sulfonamide series on Galleria mellonella (Greater wax moth)-New Approach towards Development of Biofriendly Pesticides. | National Conference on Recent Innovations in Science & Engineering at Career Point University, Hamirpur (H.P.) | - |
| 2015 | Pamita Awasthi*, Manu Vatsal, Shamsher Singh Kanwar. | Molecular modeling, structural and cytotoxic study of 1-[1-oxo-3-phenyl-(-2-benzosulfonamide- )-propyl amido] - anthracene-9,10-dione | International conference on science, technology and management | - |
| 2015 | Pamita Awasthi*, Kirna, Shilpa Dogra, Manu Vatsal, Ritu Barthwal. | Comparative in silico and in vitro study of N-(1-methyl-2-Oxo-2-N-methyl anilino-ethyl) benzene sulfonamide and its analogues as an anticancer agent Name of Conference and Dates ICC 2015: XIII International Conference on Chemistry, London, UK World academy of Science, Engineering | ICC 2015: XIII International Conference on Chemistry, London, UK World academy of Science, Engineering | - |
| 2015 | Pamita Awasthi* & Priyanka Sharma | In silico and in vivo study of phenoxy derivatives of sulfonamides as potential Juvenile Hormone Analogs against Galleria mellonella. | National Symposium on Biophysics & Golden Jubilee Meeting of Indian Biophysical Society at Centre for Interdisciplinary Research in Basic Sciences Jamia Millia Islamia, New Delhi | - |
| 2015 | Priyanka Sharma, Pamita Awasthi | Molecular modeling study of various synthetic JHAs containing varied functionality. | International Conference On Recent Trends In Engineering Science And Management (ICRTESM-2015) at Jawaharlal Nehru University (JNU, Convention Center),New Delhi | - |
| 2015 | Pamita Awasthi* & Priyanka Sharma | Synthesis, characterization and in vivo study of non terpenoids derivative of sulfonamides as Juvenile Hormone Analogs against Galleria mellonella. | National Symposium on recent trends in Nuclear Magnetic Resonance Society at GNU Amritsar | - |
| 2014 | Pamita Awasthi*, Kirna, Manu Vatsal. | Synthesis, 1HNMR, C13NMR, ESI-MASS, IR Spectral and Guassian study of N-(4-oxo-2-methyl-3-benzosulfonamide- butyl) N-Aminoanthraquinone- An anticancer Agent | National Conference on 4th National Symposium on Advances in Chemical Sciences, GNDU Amritsar , Punjab | - |
| 2014 | Pamita Awasthi*, Manu Vatsal, Kirna. | Synthesis,1H-NMR,13C NMR, ESI-MASS, IR Spectral and Gaussian study of 1-[1-oxo-3-phenyl-(-2-benzosulfonamide- )-propyl amido] - anthracene-9,10-dione to be potential anticancer agent | 51st Annual Convention of Chemist; Dec9-12, 2014. organized by : The Indian Chemical Society- Kurukshetra | - |
| 2014 | Pamita Awasthi*, Kirna, Manu Vatsal, Ritu Barthwal | 2D NMR, COSY, HSQC structural study of N-(4-oxo-2methyl-3benzosulfonamide-)N -aminoanthraquinone as an anticancer agent | Recent Trends in Chemical Sciences, Engineering and Technology | - |
| 2014 | Kirna Devi and Pamita Awasthi* | Synthesis, 1HNMR, C13NMR, ESI-MASS, IR spectral study of N-_3-oxo-3-morpholino-1-phenyl-propyl) Benzenesulfonamide as anticancer, antibacterial, antiviral, diuretic, anti-inflamatory and antifungal agent | Recent Trends in Chemical Sciences, Engineering and Technology | - |
| 2014 | Nitesh Kumar, Raj Kaushal , Ashun Chaudhary, Saroj Arora, Shrikant Kukreti, Pamita Awasthi* | In-vitro cytotoxic and calf-thymus DNA-binding studies of some titanium complexes | Recent Trends in Chemical Sciences, Engineering and Technology | - |
| 2013 | Raj Kaushal, Nitesh Kumar, Pamita Awasthi*. | Synthesis, characterization and in vitro cytotoxic studies of mixed ligand titanium complexes. | Fiftieth annual convention of chemists 2013. December 04-07, 2013. Punjab university Chandigarh. | - |
| 2013 | Raj Kaushal, Nitesh Kumar, Ashun Chaudhary, Saroj Arora, Pamita Awasthi* | Synthesis, structural elucidation and in vitro antiproliferative activities of mixed ligand titanium complexes | International conference on interdisciplinary areas with chemical sciences. | - |
| 2011 | Pamita Awasthi* & Priyanka Sharma * | In silico screening of Juvenile Hormone Analogues: a docking study | International Conference on Advances in Computing and Communication NIT Hamirpur | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | Computer Aided Designing of Juvenile Hormone Analogues as a Potential Pesticide Based on Ligand - Receptor Interaction - A Docking Study. | Conference: International Conference on Bioinformatics & Computational Biology, BIOCOMP | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | “Computer aided designing of Juvenile Hormone Analogues as a potent pesticide based on Ligand - receptor interaction - A Docking Study” | 11th International Conference on Bioinformatics and Computational Biology, | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | “Designing and Synthesis of Juvenile Hormone Analogues as a potential pesticide | Forty Seventh Annual Convention of Chemists 2010 and International Conference on Recent Advances in Chemical Sciences, Ravishankar Shukla University, Raipur | - |
| 2010 | Pamita1 Awasthi* & Shilpa Dogra1Ritu Barthwal | Research Article Synthesis, Spectral Characterization, and Antiproliferative Studies of Mixed Ligand Titanium Complexes of Adamantylamine. | Symposium on Recent Trends in Biophysics & Workshop on Emerging Techniques of Biophysics at Banaras Hindu University, Varanasi, INDIA | - |
| 2010 | Pamita Awasthi*, Priyanka Sharma and R.K.Mahanjan | Docking studies of synthesized Juvenile Hormone Analogues with its receptor sites | Symposium on Recent Trends in Biophysics & Workshop on Emerging Techniques of Biophysics at Banaras Hindu University, Varanasi, INDIA | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | In silico computational study of synthesized and proposed JHA with its receptor site | National conference on Advances in polymer Science and Technology, Hamirpur (H.P) | - |
| 2010 | Shilpa Dogra, Pamita Awasthi, | ISpectroscopic studies on interaction of mitoxantrone with poly dA-dT base pair of DNA | National conference on Advances in polymer Science and Technology, Hamirpur (H.P) | - |
| 2010 | Pamita Awasthi*, Priyanka Sharma, Shilpa Dogra, R.K. Mahajan and Ritu Barthwal | Synthesis and 2D-NMR studies of Juvenile Hormone Analogues | Symposium of recent developments and applications of Biomedical Magnetic Resonance and the 16th conference of National Magnetic Resonance Society CBMR, SGPGI, Lucknow | - |
| 2011 | Pamita Awasthi* & Priyanka Sharma * | Synthesis of Juvenile Hormone Analogues; designed feature based upon docking study. | 7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society at Indian Habitat Center, New Delhi, India | - |
| 2009 | Pamita Awasthi, Shilpa Dogra, Lalit K. Awasthi, Ritu Barthwal | Interactions of Mitoxantrone and its Analogues with DNA Tetramer Sequences- A Molecular Modeling Study. | Conference: International Conference on Bioinformatics & Computational Biology, BIOCOMP | - |
| 2006 | Ramamurthy Nagarajan, M. Diwan, Pamita Awasthi, Aviral Shukla | Optimization of Ultrasonic Cleaning for Erosion-Sensitive Microelectronic Components | Conference: Advanced Semiconductor Manufacturing Conference, 2006. ASMC | - |
Research Projects
| Role | Project Type | Title | Funding Agency | From | To | Amount | Status | Co-Investigator | Sanction Order | Sanction Date |
|---|---|---|---|---|---|---|---|---|---|---|
| Principal Investigator | Young Scientist | “Juvenile harmone Analogues as potential pesticides: Designing, synthesis, characterization, biological evaluation and field testing” | DST-SERB | 31/08/2009 | 31/07/2013 | 13 lacs | complete | nil | Anx | 31/07/2013 |
| Scientist mentor | DST-WOS-A | Synthesis, Characterization, Biological and Computational study of series of 1-[1-oxo-3-phenyl-2(benzosulfonamide)-propylamido]-anthracene-9,10-dione analogs-Anthraquinone based anticancer drugs | DST | 31/05/2017 | 30/06/2020 | 24 lacs | completed | Nil | Anx | 31/05/2017 |
| Scientist mentor | Research Project | Field Efficacy of JH mimics as Nano Pesticides: A new generation Nanocides | DST | 08/10/2021 | 08/10/2024 | 31,36, 222/- | on-going | Dr. Priyanka | DST/WOS-B/AFE-29/2021 (G) | 08/10/2021 |
Research Supervision
| Programme Name | Scholar Name | Research Topic | Status | Year | Co-Suprivisor(s) |
|---|---|---|---|---|---|
| Ph.D | Shilpa Dogra | Studies on interactions of anthraquinone based anticancer drug mitoxantrone with different DNA sequences | Completed | 2015 | Dr. Nayar |
| Ph.D | Priyanka Sharma | Computational designing, synthesis and biological evaluation of juvenile hormone analogues as a potential pesticide | Completed | 2016 | None |
| Ph.D | Nitesh Kumar | Synthesis, characterization, cytotoxic and DNA binding studies of Titanium complexes | Completed | 2016 | Dr. Raj Kaushal |
| Ph.D | Manu Vatsal | Synthesis, characterization, biological and computational studies of anthraquinine based drugs to be potential anticancer agents | Completed | 2020 | None |
| Ph.D | Ar. Veenu Shree | Study of ventilation and indoor paints in primary school classrooms of composite climate for monitoring its indoor air quality - Case study hamirpur (H.P.) | Completed | 2020 | Dr. Bhanu Marwah |
| Ph.D | Anjali Sharma | Drug-DNA interactions of synthesized analogues of anthracycline class of anticancer drugs using spectroscopic and computational tools- A novel approach to develop new class of drug candidates. | Thesis submitted | 2022 | None |
| Ph.D | Nitika Bali | Synthetic, computational and biological study of analogues of Juvenile hormone analogues to be potential Insect Growth Regulators | Ongoing | 0 | None |
| Ph.D | Kirna Devi | Synthesis, characterization, biological screening and computational studies of sulphonamide analogues to be multifunctional agents | completed | 2021 | None |
| Ph.D | Vandana Devi | Synthesis, Characterization, computational and bioassay of juvenile hormone analogues to be insect growth regulators | Completed | 2022 | None |
| Ph.D | Jaspreet | Unraveling the micellization behavior of surfactants in the presence of different additives | Thesis submitted | 2022 | Late (Dr. ) Harsh Manchanda as superviosr |
| Ph.D | Arti | Synthesis of an thraquinone and phenothiazine class of anticancer agents | on-going | 2023 | None |
Patents
| Title | Reg./Ref.No. | Date of Award/Filling | Awarding Agencies | Status |
|---|---|---|---|---|
| Juvenile Hormone Mimics for silk moth(bombex mori): Green Approach to enhance silk production | 201911047685 | 23/11/2019 | DST | Filled |
| Sulfonamide analogues to be anticancer, antibacterial, antifungal, antimicrobial, carbonic anhydrase inhibitor and antidiabetic agents | 201711028145 | 31/07/2017 | DST | Filled |
Teaching Experience
| Position Held | Department and Organization | From | To | Total Experience |
|---|---|---|---|---|
| Lecturere | Department of Applied Sciences, NIT-Hamirpur | 17/07/2005 | 27/07/2009 | 4 |
| Assistant Professor or Reader | Department of Chemistry, NIT-Hamirpur | 09/07/2009 | 09/07/2012 | 3 |
| Associate Professor | Department of Chemistry, NIT-Hamirpur | 09/07/2012 | 28/10/2020 | 8 |
Administrative Experience
| Position Held | Department and Organization | From | To |
|---|---|---|---|
| Faculty In-charge | Central Library, NIT-H | 10/04/2010 | 10/11/2012 |
| Chairperson | ICC (women cell) | 11/09/2015 | 19/02/2019 |
| warden | Ambika Girls Hostel and Parbati Girls Hostel, NIT-H | 27/07/2013 | 01/05/2018 |
| Head of the Department | Department of Chemistry, NIT-H | 15/10/2014 | 30/08/2016 |
| Head of the Department | Department of Chemical Engineering, NIT-H | 27/04/2016 | 23/04/2018 |
| Member (Senate Nominee) | Board of Governess, NIT-Hamirpur | 01/07/2016 | 01/07/2018 |
| Local Coordinator | GIAN-MHRD | 09/08/2015 | 21/02/2019 |
| Member, BOG | NIT Hamirpur | 01/07/2016 | 31/07/2018 |
| Associate Dean (FW) | NIT Hamirpur | 01/05/2018 | 31/05/2019 |
| Member Secretary | Chief Minister Star-up project | 01/09/2017 | 28/10/2020 |
| Nodal Officer | Chief Minister Star-up project | 01/12/2017 | 28/10/2020 |
Book/Chapters Written
| Type | Title | Publisher | Author(s) | ISBN/ISSN No. | Year |
|---|---|---|---|---|---|
| “Molecular Modeling Study of Interaction of Anthracene dione Class of Drug Mitoxantrone and Its Analogs with DNA Tetrameric Sequences” | Software Tools and Algorithms for Biological Systems- Advances in Experimental Medicine and Biology, 2011, Volume 696, Part 5 | Springer-Verleg. | Pamita Awasthi, Shilpa Dogra, Lalit K. Awasthi and Ritu Barthwal | ISBN 978-1-4419-7046-6 | 2011 |
Expert Talks
| Title | Place | Year | Description of Event |
|---|
Consultancy
| Title of Consultancy | Client Organization | Faculty Involved | Amount(INR) | Status |
|---|---|---|---|---|
| Completed |
International and National Exposure
| Sr.No. | Title | Description |
|---|
Conferences/Courses Organized
| Category | Type | Title | Venue | From | To | Designation |
|---|---|---|---|---|---|---|
| stc | Chemical Engineering Department | Short Term Course on Learning CFD using ANSYS | NIT-Hamirpur | 16/05/2017 | 21/05/2017 | Coordinator |
| stc | Chemical Engineering Department NIT-Hamirpur | Short Term Course on computation Fluid dynamics and Heat Transfer | NIT-Hamirpur | 05/09/2016 | 10/09/2016 | Co-Chairman |
| stc | JNGEC, Sunder Nagar | One week Induction Training Program | Sunder Nagar | 02/08/2014 | 06/08/2014 | Convener |
| stc | Chemical Engineering Department | Fundamentals of fluid mechanics and its application in industry | NIT-Hamirpur | 17/09/2017 | 22/12/2017 | Organizing secretary |
| stc | Department of CSE | Short Term course on Sensor Based Embedded Systems Design (SESD-2016) | NIT-Hamirpur | 18/07/2016 | 29/07/2016 | Local Coordinator GIAN |
| stc | Department of Chemistry | Short Term Course on Advanced Nanomaterials: Applications in Disease Diagnosis and Imaging | NIT-Hamirpur | 30/05/2016 | 03/06/2016 | Local Coordinator GIAN |
| stc | Department of Civil Engineering | Short term Course on Characterizing the uncertainties in climate change impacts assessment for water resources | NIT-Hamirpur | 22/02/2016 | 26/01/2016 | Local Coordinator GIAN |
| stc | Department of Civil Engineering | Landslide hazards and related phenomena | NIT-Hamirpur | 16/05/2016 | 20/05/2016 | Local Coordinator GIAN |
| stc | Department of Electrical Engineering | PMSM and BLDC motor drive system | NIT-Hamirpur | 18/12/2017 | 29/12/2017 | Local Coordinator GIAN |
| stc | Department of Applied science | STC Under community development on challenges and opportunities in sci. and technology | NIT-Hamirpur | 14/06/2010 | 18/06/2010 | Co-Coordinator |
| stc | Department of Chemistry | Short Term Course Chemical and Biochemical and Environmental issues related to cancer and solutions addressing the problem under GIAN | NIT-Hamirpur | 11/09/2017 | 17/09/2017 | Local coordinator And Course coordinator |
| stc | Chemical Engineering Department | Emerging electrical energy storage application | NIT-Hamirpur | 11/12/2017 | 16/12/2016 | Local coordinator and Course coordinator |
| stc | Chemical Engineering Department | Industrial waste and hazard management | NIT-Hamirpur | 15/01/2018 | 20/01/2018 | Coordinator |
| stc | Department of Civil Engineering | Structural health monitoring by full-filed measurement technique and simulation model. | NIT-Hamirpur | 16/06/2018 | 22/06/2018 | Local coordinator |
| stc | Department of Chemistry | Challenges and opportunities in science and Technology | NIT-Hamirpur | 14/06/2010 | 18/06/2010 | Co-cordinator |
| stc | Department of Chemistry | Short Term Course Chemical and Biochemical and Environmental issues related to cancer and solutions addressing the problem | NIT-Hamirpur | 11/09/2017 | 16/09/2017 | Course coordinator |
| stc | Department of Chemical Engineering | Emerging electrical energy storage application | NIT-Hamirpur | 11/12/2017 | 16/12/2017 | Course coordinator |
| conference | Chemical Engineering Department | National Conference on Recent Trends in Chemical Sciences and Engineering RTCSE-2017 | NIT-Hamirpur | 13/10/2017 | 14/10/2017 | Co-Chairman |
| conference | Chemistry Department | National Conference on Analytical Chemistry and Molecular Spectroscopy | NIT-Hamirpur | 01/10/2016 | 01/10/2016 | Co-Chairman |
| conference | Chemistry Department | National Conference on Recent Trends in Chemical Sciences, Engineering and Technology (RTCET 2014) | NIT-Hamirpur | 29/05/2014 | 30/05/2014 | Co-convener |
| conference | Chemistry Department | Advances in polymer science and technology-APST-2010 | NIT-Hamirpur | 22/10/2010 | 24/10/2010 | Convener |
Profile Summary
Last Update: 27/01/2023 09:25pm
| Name | : | Dr. Pamita Awasthi |
| Designation | : | Associate Professor |
| Department | : | Chemistry |
| Qualification | : | Ph.D |
| Phone | : | 254140 |
| Email ID | : | pamita@nith.ac.in |
| Profile URL | : | https://portfolios.nith.ac.in/index.php?/nith/dr-pamita-awasthi145 |
| Date of Birth | : | 10/03/1972 |
| Date of Joining | : | 27/07/2007 |
Specialization
Chemistry
Education Qualification
| Name of the Degree | Year of Passing | Institute/University |
|---|---|---|
| Ph.D | 2000 | Chemistry Department, Himachal Pradesh University, Shimla |
| M.Sc | 1994 | Chemistry Department, Himachal Pradesh University, Shimla |
| B.Sc (Hons.) | 1992 | St. Bede's Collage Shimla |
| Post Doctoral | 2003 | Department of Biotechnology, IIT- Roorkee |
Teaching Experience
| Programme Name | Department And Organization | From | To | Total Experience |
|---|---|---|---|---|
| Lecturere | Department of Applied Sciences, NIT-Hamirpur | 17/07/2005 | 27/07/2009 | 4 |
| Assistant Professor or Reader | Department of Chemistry, NIT-Hamirpur | 09/07/2009 | 09/07/2012 | 3 |
| Associate Professor | Department of Chemistry, NIT-Hamirpur | 09/07/2012 | 28/10/2020 | 8 |
Administrative Experience
| Position Held | Department And Organization | From | To |
|---|---|---|---|
| Faculty In-charge | Central Library, NIT-H | 10/04/2010 | 10/11/2012 |
| Chairperson | ICC (women cell) | 11/09/2015 | 19/02/2019 |
| warden | Ambika Girls Hostel and Parbati Girls Hostel, NIT-H | 27/07/2013 | 01/05/2018 |
| Head of the Department | Department of Chemistry, NIT-H | 15/10/2014 | 30/08/2016 |
| Head of the Department | Department of Chemical Engineering, NIT-H | 27/04/2016 | 23/04/2018 |
| Member (Senate Nominee) | Board of Governess, NIT-Hamirpur | 01/07/2016 | 01/07/2018 |
| Local Coordinator | GIAN-MHRD | 09/08/2015 | 21/02/2019 |
| Member, BOG | NIT Hamirpur | 01/07/2016 | 31/07/2018 |
| Associate Dean (FW) | NIT Hamirpur | 01/05/2018 | 31/05/2019 |
| Member Secretary | Chief Minister Star-up project | 01/09/2017 | 28/10/2020 |
| Nodal Officer | Chief Minister Star-up project | 01/12/2017 | 28/10/2020 |
Research Experience
| Research Interests : | 1. Synthesis of natural product mimics (Juvenile hormone analogues- A sesquiterpieoide class of compounds; 9,10 anthraquinone class of anticancer candidates) 2. Bioassay and biophysical studies on ligand- receptor interaction. 3. Semiemperical and quantum chemical studies on small molecules using computation chemistry tools. 4. 2D -NMR structural configuration of small molecules | |
| Brief Research Statement : |
Research Projects
| Role | Project Type | Title | Funding Agency | From | To | Amount | Status | Co-Investigator | Sanction Order | Sanction Date |
|---|---|---|---|---|---|---|---|---|---|---|
| Principal Investigator | Young Scientist | “Juvenile harmone Analogues as potential pesticides: Designing, synthesis, characterization, biological evaluation and field testing” | DST-SERB | 31/08/2009 | 31/07/2013 | 13 lacs | complete | nil | Anx | 31/07/2013 |
| Scientist mentor | DST-WOS-A | Synthesis, Characterization, Biological and Computational study of series of 1-[1-oxo-3-phenyl-2(benzosulfonamide)-propylamido]-anthracene-9,10-dione analogs-Anthraquinone based anticancer drugs | DST | 31/05/2017 | 30/06/2020 | 24 lacs | completed | Nil | Anx | 31/05/2017 |
| Scientist mentor | Research Project | Field Efficacy of JH mimics as Nano Pesticides: A new generation Nanocides | DST | 08/10/2021 | 08/10/2024 | 31,36, 222/- | on-going | Dr. Priyanka | DST/WOS-B/AFE-29/2021 (G) | 08/10/2021 |
Journal Publications
| Year | Author(s) | Journal Name | Title & Vol. No. | Indexing (SCI/Web of science/Scopus) |
|---|---|---|---|---|
| 2022 | Anjali Sharma, Pamita Awasthi | Journal of Chemical Sciences | Synthesis, cytotoxic evaluation and ct-DNA binding of series of 1, 4-disubstituted anthraquinone-sulfonamide conjugates | - |
| 2022 | Kirna Devi, Pamita Awasthi | Journal of Biomolecular Structure and Dynamics | Isoleucine with secondary sulfonamide functionality as anticancer, antibacterial and antifungal agents | - |
| 2022 | Harsh Kumar, Jasmeet Kaur, Pamita Awasthi | Colloids and Surfaces A: Physicochemical and Engineering Aspects | Investigation of aggregation and surface active properties of cationic Gemini surfactants in the presence of antidepressant drug | - |
| 2022 | Vandna Devi, Neetika Kumari, Pamita Awasthi | Phosphorus, Sulfur, and Silicon and the Related Elements | Synthesis, characterization and insect growth regulating study of beta-alanine substituted sulfonamide derivatives as juvenile hormone mimics | - |
| 2022 | Vandna Devi, Pamita Awasthi | Journal of Molecular Structure | Synthesis, structural, DFT and bio-assay of novel ethyl 3-(2-(4-chlorophenoxy) acetamido) propanoate on Galleria mellonela (wax moth)–a juvenile hormone mimic as potential | - |
| 2021 | Vandna Devi, Pamita Awasthi | Journal of Biomolecular Structure and Dynamics | Juvenile hormone mimics with phenyl ether and amide functionality to be insect growth regulators (IGRs): synthesis, characterization, computational and biological study | - |
| 2021 | Harsh Kumar, Jasmeet Kaur, Pamita Awasthi | Journal of Molecular Liquids | Scrutinizing the Micellization Behaviour of 14-2-14 Gemini Surfactant and Tetradecyltrimethylammonium Bromide in Aqueous Solutions of Betaine Hydrochloride | - |
| 2021 | Sharma, Pamita Awasthi | Journal of Molecular Structure | Synthesis, characterization, in vivo, molecular docking, ADMET and HOMO-LUMO study of Juvenile hormone analogues having sulfonamide feature as an insect growth regulators. | - |
| 2021 | Pamita Awasthi, Anjali Sharma, Manu Vatsal | Journal of Molecular Structure | Spectroscopic, viscometric and computational binding study of 1 and 2 substituted anthraquinone analogs to be potential anti-cancer agents. | - |
| 2020 | Kirna Devi, Pamita Awasthi | Journal of Biomolecular Structure and Dynamics | Sulfonamide phenylalanine (SPA) series of analogues as an antibacterial, antifungal, anticancer agents along with p53 tumor suppressor-DNA complex inhibitor–part | - |
| 2020 | Manpreet Singh, Pamita Awasthi, Virender Singh | European Journal of Organic Chemistry | Iodine Catalysed Synthesis of Luminescent β‐Carboline Tethered Thiazolo[4,5‐c]carbazole and Naphtho[2,1‐d]thiazole Derivatives and Estimation of their Light | - |
| 2019 | Pamita Awasthi, Manu Vatsal, Anjali Sharma | Journal of Biomolecular Structure and Dynamics | Structural and biological study of synthesized anthraquinone series of compounds with sulfonamide feature. | - |
| 2019 | Pamita Awasthi, Kirna Devi | Research on Chemical Intermediates | Structural characterization, photoluminescence, computational studies and bioassay of newly synthesized N-(3-oxo-3-morpholino-1-phenyl-propyl) benzo sulfonamide with | - |
| 2018 | Nitesh Kumar, Raj Kaushal, Ashun Chaudhary, Saroj Arora, Pamita Awasthi | Inorganic and Nano-Metal Chemistry | Titanium based mixed ligand complexes: Synthesis, spectroscopic and in vitro antiproliferative studies. | - |
| 2018 | Manu Vatsal, Vandna Devi, Pamita Awasthi | Journal of Molecular Structure | Structural and theoretical study of 1-[1-oxo-3-phenyl-(2-benzosulfonamide)-propyl amido]–anthracene-9, 10-dione to be i-motif inhibitor. | - |
| 2018 | Raj Kaushal, Nitesh Kumar, Archana Thakur, Kiran Nehra, Pamita Awasthi, Rajeev Kaushal, Saroj Arora | Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents) | Synthesis, spectral characterization, antibacterial and anticancer activity of some titanium complexes. | - |
| 2016 | Priyanka Sharma, Sunil Thakur, Pamita Awasthi | Journal of Biomolecular Structure and Dynamics | In silico and bio assay of juvenile hormone analogs as an insect growth regulator against Galleria mellonella (wax moth) – Part I. | - |
| 2015 | Pamita Awasthi, Nitesh Kumar, Raj Kaushal, Mohan Kumar, Shrikant Kukreti | Biochemistry research international | Comparative In Vitro Binding Studies of TiCl2 (dpme) 2, Ti (ada) 2 (bzac) 2, and TiCl2 (bzac)(bpme) Titanium Complexes with Calf-Thymus DNA. | - |
| 2015 | Priyanka Sharma, Sunil Thakur, Pamita Awasthi | Applied biochemistry and biotechnology | Synthesis, characterization, biological evaluation and docking study of heterocyclic-based synthetic sulfonamides as potential pesticide against G. mellonella. | - |
| 2015 | Pamita Awasthi, Nitesh Kumar, Raj Kaushal, Mohan Kumar, Shrikant Kukreti | Biochemistry Research International | Comparative in vitro binding studies of Ti [Cl. sub. 2][(dpme). sub. 2], Ti [(ada). sub. 2][(bzac). sub. 2], and Ti [Cl. sub. 2](bzac)(bpme) titanium complexes with calf-thymus DNA. | - |
| 2014 | Nitesh Kumar, Raj Kaushal, Ashun Chaudhary, Saroj Arora, Pamita Awasthi | Medicinal Chemistry Research | Synthesis, structural elucidation, and in vitro antiproliferative activities of mixed-ligand titanium complexes. | - |
| 2014 | Shilpa Dogra, Pamita Awasthi, Sweta Tripathi, TP Pradeep, Maya S Nair, Ritu Barthwal | Journal of Biomolecular Structure and Dynamics | NMR-based structure of anticancer drug mitoxantrone stacked with terminal base pair of DNA hexamer sequence d-(ATCGAT)2 | - |
| 2014 | Raj Kaushal, Nitesh Kumar, Ashun Chaudhary, Saroj Arora, Pamita Awasthi | Bioinorganic Chemistry and Applications | Research Article Synthesis, Spectral Characterization, and Antiproliferative Studies of Mixed Ligand Titanium Complexes of Adamantylamine. | - |
| 2013 | Pamita Awasthi, Shilpa Dogra, Ritu Barthwal | Journal of Photochemistry and Photobiology B: Biology | Multispectroscopic methods reveal different modes of interaction of anti cancer drug mitoxantrone with Poly (dG-dC). Poly (dG-dC) and Poly (dA-dT). Poly (dA-dT). | - |
| 2013 | Shilpa Dogra, Pamita Awasthi, Maya Nair, Ritu Barthwal | Journal of Photochemistry and Photobiology B: Biology | Interaction of anticancer drug mitoxantrone with DNA hexamer sequence d-(CTCGAG) 2 by absorption, fluorescence and circular dichroism spectroscopy. | - |
| 2013 | A Pamita, S Priyanka | Journal of Computer Science and Systems Biology | Designing and binding mode prediction of juvenile hormone analogues as potential inhibitor for Galleria mellonella. | - |
| 2013 | Raj Kaushal, Nitesh Kumar, Pamita Awasthi, Kiran Nehra | Turkish Journal of Chemistry | Syntheses, characterization, and antibacterial study of titanium complexes. | - |
| 2013 | Shilpa Dogra, Pamita Awasthi, Barthwal Ritu | nternational Journal of Current Research and Review | Comparative Molecular Modeling Study of Binding of Mitoxantrone with d-(ATCGAT) 2 and d-(CTCGAG) 2 Hexamer DNA Sequences | - |
| 2013 | Pamita Awasthi, Shilpa Dogra, Lalit K Awasthi, Ritu Barthwal | International Journal of Drug Design and Discovery | Interaction of Mitoxantrone and its Analogs with Methylated and Non-methylated CpG Islands in Tetrameric DNA Sequences: A Molecular Modeling Study . | - |
| 2012 | P Awasthi, P Sharma | Taylor & Francis Group : SAR and QSAR in Environmental Research | In silico screening of the juvabione category of juvenile hormone analogues with juvenile hormone binding protein of Galleria mellonella – a docking study. | - |
| 2011 | R Kaushal, N Kumar, R Kaushal, P Awasthi | Int J Curr Res Rev | An insight into metal based anti-cancer drugs. | - |
| 2008 | Pamita Awasthi, RK Mahajan | Synthesis of some sulphonamide insect juvenile hormone-Part I | Synthesis of some sulphonamide insect juvenile hormone - Part I | - |
| 2006 | Ritu Barthwal, Uma Sharma, Nandana Srivastava, Monica Jain, Pamita Awasthi, Manpreet Kaur, Sudhir Kumar Barthwal, Girjesh Govil | European journal of medicinal chemistry | Structure of daunomycin complexed to d-TGATCA by two-dimensional nuclear magnetic resonance spectroscopy | - |
| 2004 | Ritu Barthwal, Pamita Awasthi, Manpreet Kaur, Uma Sharma, Nandana Srivastava, SK Barthwal, Girjesh Govil | Journal of structural biology | Structure of DNA sequence d-TGATCA by two-dimensional nuclear magnetic resonance spectroscopy and restrained molecular dynamics. | - |
| 2003 | Ritu Barthwal, Monica, Pamita Awasthi, Nandana Srivastava, Uma Sharma, Manpreet Kaur, Girjesh Govil | Journal of Biomolecular Structure and Dynamics | Structure of DNA hexamer sequence d-CGATCG by two-dimensional nuclear magnetic resonance spectroscopy and restrained molecular dynamics | - |
| 2002 | Ved Parkash Patial and Pamita Sharma R.K.Mahajan | CSIR-NISCAIR : Indian Journal of Chemistry | Juvenile Hormone like substances: Part XV-Synthesis and biological activities of some juvenile hormone analogues containing sulphonamide feature. | - |
Conference Publications
| Year | Author(s) | Conference | Title | Indexing |
|---|---|---|---|---|
| 2021 | Neetika Kumari, Vandna Devi, Pamita Awasthi | 27 th International Conference of International Academy of Physical Sciences (CONIAPS XXVIII) On "Recent Advances in Catalysis Science & Engineering (RACSE)" | Quantum Chemical and Molecular Docking Study of commercially used Insect Growth Regulators | - |
| 2021 | Anjali Sharma, Pamita Awasthi | 27 th International Conference of International Academy of Physical Sciences (CONIAPS XXVIII) On "Recent Advances in Catalysis Science & Engineering (RACSE)" | Comparative computational docking study of Mitoxantrone and 2-[1-oxo- 3-phenyl-2-(benzosulfonamide)-propylamido]-anthracene-9,10-dione (B1) with parallel G- Quaderuplex DNA (d-(TTGGGGT)4) fragment of telomeric junction | - |
| 2018 | Anjali Sharma, Manu Vatsal, Ankush Thakur, Aditya Goyal, Kamlesh Kumar, Monika Guleria, Rakesh Ranjan, Sachin Tiwari, Pamita Awasthi | 71th Annual Session of Indian Institute of Chemical Engineers Seamless Chemical Engineering in service of Humanity: Innovations, Opportunities & Challenges (CHEMCON–2018), Department of Chemical Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar. | Interaction study of 9(10H)-acridanone with ct-DNA using UV-Visible, Fluorescence & Viscometric techniques | - |
| 2018 | Manu Vatsal, Anjali Sharma, Vikas Kumar, Sushil kumar, Dilip Garg, Rahul Yadav, Udit Khandara, Rajesh Kumar, Pamita Awasthi | BICON-2018, Biyani Girls College, Jaipur. | Atomic interaction pattern of anthraquinone with polyAT.polyAT sequence | - |
| 2018 | Vandna Devi, Pamita Awasthi | 71th Annual Session of Indian Institute of Chemical Engineers Seamless Chemical Engineering in Service of Humanity: Innovations, Opportunities & Challenges (CHEMCON-2018) | Structural and theoretical study of N-[3-oxoanilino-propyl]benzene sulfonamide to be insect growth regulators : A quantum chemical approach | - |
| 2018 | Raj Kaushal, Nitesh Kumar, Kiran Nehra, Pamita Awasthi*. | National Symposium on Biotechnology: Present Status and Future Prospectus. March 15-16, 2013. Deenbandhu Chotu Ram University of Science and Technology Murthal, Sonepat-131039. (copy not enclosed) Best oral presentation award | Synthesis, Characterization and Antibacterial Study of Titanium(IV) Complexes. | - |
| 2018 | Nitesh Kumar1, Raj Kaushal1, Saroj 2 Arora, shrikant kukreti 3 Pamita Awasthi | Recent development in chemical sciences and technology: Yound scientist meet. NIT-Rourkela | Synthesis, Characterization, Cytotoxic and DNA binding studies of titanium complexes | - |
| 2017 | Kirna Devi and Pamita Awasthi* | Recent Trends in Chemical Sciences And Engineering 13-14 Oct. 2017 at NIT- Hamirpur (H.P) | Synthesis, Spectral and Docking studies of New Sulfonamide Compounds | - |
| 2017 | Pamita Awasthi* and Vandana Devi | Recent Trends in Chemical Sciences And Engineering 13-14 Oct. 2017 NIT- Hamirpur (H.P) | Thermodynamic, Docking study and Structural Analysis of N-(6methyl-2-oxo-3-oxa-heptanyl) Benzene Sulfonamide and Juvenile Hormone as Insect growth regulators | - |
| 2017 | Manu Vatsal, Anjali Sharma, S.S.Kanwar, Ritu Kapoor, Pamita Awasthi* | Recent Trends inChemical Sciences And Engineering 13-14 Oct. 2017 NIT- Hamirpur (H.P) | MIC for determination of Antibacterial behavior of suffonamide derivatives: A quantum Chemical Approach | - |
| 2017 | Kirna Devi and Pamita Awasthi* | National conference on role of biophysics in academia and industry, Punjab University | Synthesis, Characterization, molecular simulation, antibacterial and antiofungal activities of new sulfonamide compounds | - |
| 2017 | PamitaAwasthi*, Vandna, Manu Vatsal, Kirna Devi | Recent trends in plant and environmental science | Thermodynamic and structural study of n-(1-isopropyl-2-oxo-3-aza-butanyl)benz ene sulfonamide and1-[1-oxo-3-phenyl-2-(p-tosylamide)-propylamido] anthracene9, 10 dione. | - |
| 2017 | Manu vatsal; Pamita Awasthi | NanoSciTech2017, 8-10 Nov. 2017 PU, Chandigarh | Molecular modeling of 1{1-oxo-3(3-methyl-2)p-tosylamide)-butyl amido]-anthracene 9,10-dione with d(TCCCCC) to be i-motif inhibitor | - |
| 2017 | Priyanka Sharma and Pamita Awasthi | National Conference on Advances in Basic & Applied Sciences at Career Point University, Hamirpur (H.P.) | Comparative Molecular Modelling of Various Non-terpenoids JHAs against Insect pests. | - |
| 2016 | Pamita Awasthi*, Manu Vatsal | International conference on Improving Quality of life using nanotechnology: Potential role of polymers at Panjab University | Molecular docking study of1-[1-oxo-3-phenyl-(-2-benzosulfonamide-)-propyl amido] - anthracene-9, 10-dione with ds-DNA to be a potential anticancer agent in Improving Quality of life using nanotechnology | - |
| 2016 | Pamita Awasthi* & Priyanka Sharma | 14th International Conference on Modelling and Simulation, (UKSim) - 2012. Cambridge University | “Docking Study of Synthesized Juvenile Hormone Analogues as an Insect Growth 27Regulators” Growth Regulators” | - |
| 2016 | Priyanka Sharma, Pamita Awasthi | National Conference on Recent Innovations in Science & Engineering at Career Point University, Hamirpur (H.P.) | Comparative Insect Growth Regulators Effect of two sulfonamide series on Galleria mellonella (Greater wax moth)-New Approach towards Development of Biofriendly Pesticides. | - |
| 2015 | Pamita Awasthi*, Manu Vatsal, Shamsher Singh Kanwar. | International conference on science, technology and management | Molecular modeling, structural and cytotoxic study of 1-[1-oxo-3-phenyl-(-2-benzosulfonamide- )-propyl amido] - anthracene-9,10-dione | - |
| 2015 | Pamita Awasthi*, Kirna, Shilpa Dogra, Manu Vatsal, Ritu Barthwal. | ICC 2015: XIII International Conference on Chemistry, London, UK World academy of Science, Engineering | Comparative in silico and in vitro study of N-(1-methyl-2-Oxo-2-N-methyl anilino-ethyl) benzene sulfonamide and its analogues as an anticancer agent Name of Conference and Dates ICC 2015: XIII International Conference on Chemistry, London, UK World academy of Science, Engineering | - |
| 2015 | Pamita Awasthi* & Priyanka Sharma | National Symposium on Biophysics & Golden Jubilee Meeting of Indian Biophysical Society at Centre for Interdisciplinary Research in Basic Sciences Jamia Millia Islamia, New Delhi | In silico and in vivo study of phenoxy derivatives of sulfonamides as potential Juvenile Hormone Analogs against Galleria mellonella. | - |
| 2015 | Priyanka Sharma, Pamita Awasthi | International Conference On Recent Trends In Engineering Science And Management (ICRTESM-2015) at Jawaharlal Nehru University (JNU, Convention Center),New Delhi | Molecular modeling study of various synthetic JHAs containing varied functionality. | - |
| 2015 | Pamita Awasthi* & Priyanka Sharma | National Symposium on recent trends in Nuclear Magnetic Resonance Society at GNU Amritsar | Synthesis, characterization and in vivo study of non terpenoids derivative of sulfonamides as Juvenile Hormone Analogs against Galleria mellonella. | - |
| 2014 | Pamita Awasthi*, Kirna, Manu Vatsal. | National Conference on 4th National Symposium on Advances in Chemical Sciences, GNDU Amritsar , Punjab | Synthesis, 1HNMR, C13NMR, ESI-MASS, IR Spectral and Guassian study of N-(4-oxo-2-methyl-3-benzosulfonamide- butyl) N-Aminoanthraquinone- An anticancer Agent | - |
| 2014 | Pamita Awasthi*, Manu Vatsal, Kirna. | 51st Annual Convention of Chemist; Dec9-12, 2014. organized by : The Indian Chemical Society- Kurukshetra | Synthesis,1H-NMR,13C NMR, ESI-MASS, IR Spectral and Gaussian study of 1-[1-oxo-3-phenyl-(-2-benzosulfonamide- )-propyl amido] - anthracene-9,10-dione to be potential anticancer agent | - |
| 2014 | Pamita Awasthi*, Kirna, Manu Vatsal, Ritu Barthwal | Recent Trends in Chemical Sciences, Engineering and Technology | 2D NMR, COSY, HSQC structural study of N-(4-oxo-2methyl-3benzosulfonamide-)N -aminoanthraquinone as an anticancer agent | - |
| 2014 | Kirna Devi and Pamita Awasthi* | Recent Trends in Chemical Sciences, Engineering and Technology | Synthesis, 1HNMR, C13NMR, ESI-MASS, IR spectral study of N-_3-oxo-3-morpholino-1-phenyl-propyl) Benzenesulfonamide as anticancer, antibacterial, antiviral, diuretic, anti-inflamatory and antifungal agent | - |
| 2014 | Nitesh Kumar, Raj Kaushal , Ashun Chaudhary, Saroj Arora, Shrikant Kukreti, Pamita Awasthi* | Recent Trends in Chemical Sciences, Engineering and Technology | In-vitro cytotoxic and calf-thymus DNA-binding studies of some titanium complexes | - |
| 2013 | Raj Kaushal, Nitesh Kumar, Pamita Awasthi*. | Fiftieth annual convention of chemists 2013. December 04-07, 2013. Punjab university Chandigarh. | Synthesis, characterization and in vitro cytotoxic studies of mixed ligand titanium complexes. | - |
| 2013 | Raj Kaushal, Nitesh Kumar, Ashun Chaudhary, Saroj Arora, Pamita Awasthi* | International conference on interdisciplinary areas with chemical sciences. | Synthesis, structural elucidation and in vitro antiproliferative activities of mixed ligand titanium complexes | - |
| 2011 | Pamita Awasthi* & Priyanka Sharma * | International Conference on Advances in Computing and Communication NIT Hamirpur | In silico screening of Juvenile Hormone Analogues: a docking study | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | Conference: International Conference on Bioinformatics & Computational Biology, BIOCOMP | Computer Aided Designing of Juvenile Hormone Analogues as a Potential Pesticide Based on Ligand - Receptor Interaction - A Docking Study. | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | 11th International Conference on Bioinformatics and Computational Biology, | “Computer aided designing of Juvenile Hormone Analogues as a potent pesticide based on Ligand - receptor interaction - A Docking Study” | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | Forty Seventh Annual Convention of Chemists 2010 and International Conference on Recent Advances in Chemical Sciences, Ravishankar Shukla University, Raipur | “Designing and Synthesis of Juvenile Hormone Analogues as a potential pesticide | - |
| 2010 | Pamita1 Awasthi* & Shilpa Dogra1Ritu Barthwal | Symposium on Recent Trends in Biophysics & Workshop on Emerging Techniques of Biophysics at Banaras Hindu University, Varanasi, INDIA | Research Article Synthesis, Spectral Characterization, and Antiproliferative Studies of Mixed Ligand Titanium Complexes of Adamantylamine. | - |
| 2010 | Pamita Awasthi*, Priyanka Sharma and R.K.Mahanjan | Symposium on Recent Trends in Biophysics & Workshop on Emerging Techniques of Biophysics at Banaras Hindu University, Varanasi, INDIA | Docking studies of synthesized Juvenile Hormone Analogues with its receptor sites | - |
| 2010 | Pamita Awasthi* & Priyanka Sharma | National conference on Advances in polymer Science and Technology, Hamirpur (H.P) | In silico computational study of synthesized and proposed JHA with its receptor site | - |
| 2010 | Shilpa Dogra, Pamita Awasthi, | National conference on Advances in polymer Science and Technology, Hamirpur (H.P) | ISpectroscopic studies on interaction of mitoxantrone with poly dA-dT base pair of DNA | - |
| 2010 | Pamita Awasthi*, Priyanka Sharma, Shilpa Dogra, R.K. Mahajan and Ritu Barthwal | Symposium of recent developments and applications of Biomedical Magnetic Resonance and the 16th conference of National Magnetic Resonance Society CBMR, SGPGI, Lucknow | Synthesis and 2D-NMR studies of Juvenile Hormone Analogues | - |
| 2011 | Pamita Awasthi* & Priyanka Sharma * | 7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society at Indian Habitat Center, New Delhi, India | Synthesis of Juvenile Hormone Analogues; designed feature based upon docking study. | - |
| 2009 | Pamita Awasthi, Shilpa Dogra, Lalit K. Awasthi, Ritu Barthwal | Conference: International Conference on Bioinformatics & Computational Biology, BIOCOMP | Interactions of Mitoxantrone and its Analogues with DNA Tetramer Sequences- A Molecular Modeling Study. | - |
| 2006 | Ramamurthy Nagarajan, M. Diwan, Pamita Awasthi, Aviral Shukla | Conference: Advanced Semiconductor Manufacturing Conference, 2006. ASMC | Optimization of Ultrasonic Cleaning for Erosion-Sensitive Microelectronic Components | - |
Book/Chapters Written
| Type (Book/Chapter) | Author(s) | Title | Publisher | ISBN/ISSN No. | Year |
|---|---|---|---|---|---|
| “Molecular Modeling Study of Interaction of Anthracene dione Class of Drug Mitoxantrone and Its Analogs with DNA Tetrameric Sequences” | Pamita Awasthi, Shilpa Dogra, Lalit K. Awasthi and Ritu Barthwal | Software Tools and Algorithms for Biological Systems- Advances in Experimental Medicine and Biology, 2011, Volume 696, Part 5 | Springer-Verleg. | ISBN 978-1-4419-7046-6 | 2011 |
Research Supersion
| Programme Name | Scholar Name | Research Topic | Status | Year | Co-Superivisor(s) |
|---|---|---|---|---|---|
| Ph.D | Shilpa Dogra | Studies on interactions of anthraquinone based anticancer drug mitoxantrone with different DNA sequences | Completed | 2015 | Dr. Nayar |
| Ph.D | Priyanka Sharma | Computational designing, synthesis and biological evaluation of juvenile hormone analogues as a potential pesticide | Completed | 2016 | None |
| Ph.D | Nitesh Kumar | Synthesis, characterization, cytotoxic and DNA binding studies of Titanium complexes | Completed | 2016 | Dr. Raj Kaushal |
| Ph.D | Manu Vatsal | Synthesis, characterization, biological and computational studies of anthraquinine based drugs to be potential anticancer agents | Completed | 2020 | None |
| Ph.D | Ar. Veenu Shree | Study of ventilation and indoor paints in primary school classrooms of composite climate for monitoring its indoor air quality - Case study hamirpur (H.P.) | Completed | 2020 | Dr. Bhanu Marwah |
| Ph.D | Anjali Sharma | Drug-DNA interactions of synthesized analogues of anthracycline class of anticancer drugs using spectroscopic and computational tools- A novel approach to develop new class of drug candidates. | Thesis submitted | 2022 | None |
| Ph.D | Nitika Bali | Synthetic, computational and biological study of analogues of Juvenile hormone analogues to be potential Insect Growth Regulators | Ongoing | 0 | None |
| Ph.D | Kirna Devi | Synthesis, characterization, biological screening and computational studies of sulphonamide analogues to be multifunctional agents | completed | 2021 | None |
| Ph.D | Vandana Devi | Synthesis, Characterization, computational and bioassay of juvenile hormone analogues to be insect growth regulators | Completed | 2022 | None |
| Ph.D | Jaspreet | Unraveling the micellization behavior of surfactants in the presence of different additives | Thesis submitted | 2022 | Late (Dr. ) Harsh Manchanda as superviosr |
| Ph.D | Arti | Synthesis of an thraquinone and phenothiazine class of anticancer agents | on-going | 2023 | None |
Patents
| Name | Reg./Ref.No. | Date of Award/Filling | Awarding Agencies | Status |
|---|---|---|---|---|
| Juvenile Hormone Mimics for silk moth(bombex mori): Green Approach to enhance silk production | 201911047685 | 23/11/2019 | DST | Filled |
| Sulfonamide analogues to be anticancer, antibacterial, antifungal, antimicrobial, carbonic anhydrase inhibitor and antidiabetic agents | 201711028145 | 31/07/2017 | DST | Filled |
Conferences/Workshop/Courses Organized
| Category | Type | Title | Venue | From | To | Designation |
|---|---|---|---|---|---|---|
| stc | Chemical Engineering Department | Short Term Course on Learning CFD using ANSYS | NIT-Hamirpur | 16/05/2017 | 21/05/2017 | Coordinator |
| stc | Chemical Engineering Department NIT-Hamirpur | Short Term Course on computation Fluid dynamics and Heat Transfer | NIT-Hamirpur | 05/09/2016 | 10/09/2016 | Co-Chairman |
| stc | JNGEC, Sunder Nagar | One week Induction Training Program | Sunder Nagar | 02/08/2014 | 06/08/2014 | Convener |
| stc | Chemical Engineering Department | Fundamentals of fluid mechanics and its application in industry | NIT-Hamirpur | 17/09/2017 | 22/12/2017 | Organizing secretary |
| stc | Department of CSE | Short Term course on Sensor Based Embedded Systems Design (SESD-2016) | NIT-Hamirpur | 18/07/2016 | 29/07/2016 | Local Coordinator GIAN |
| stc | Department of Chemistry | Short Term Course on Advanced Nanomaterials: Applications in Disease Diagnosis and Imaging | NIT-Hamirpur | 30/05/2016 | 03/06/2016 | Local Coordinator GIAN |
| stc | Department of Civil Engineering | Short term Course on Characterizing the uncertainties in climate change impacts assessment for water resources | NIT-Hamirpur | 22/02/2016 | 26/01/2016 | Local Coordinator GIAN |
| stc | Department of Civil Engineering | Landslide hazards and related phenomena | NIT-Hamirpur | 16/05/2016 | 20/05/2016 | Local Coordinator GIAN |
| stc | Department of Electrical Engineering | PMSM and BLDC motor drive system | NIT-Hamirpur | 18/12/2017 | 29/12/2017 | Local Coordinator GIAN |
| stc | Department of Applied science | STC Under community development on challenges and opportunities in sci. and technology | NIT-Hamirpur | 14/06/2010 | 18/06/2010 | Co-Coordinator |
| stc | Department of Chemistry | Short Term Course Chemical and Biochemical and Environmental issues related to cancer and solutions addressing the problem under GIAN | NIT-Hamirpur | 11/09/2017 | 17/09/2017 | Local coordinator And Course coordinator |
| stc | Chemical Engineering Department | Emerging electrical energy storage application | NIT-Hamirpur | 11/12/2017 | 16/12/2016 | Local coordinator and Course coordinator |
| stc | Chemical Engineering Department | Industrial waste and hazard management | NIT-Hamirpur | 15/01/2018 | 20/01/2018 | Coordinator |
| stc | Department of Civil Engineering | Structural health monitoring by full-filed measurement technique and simulation model. | NIT-Hamirpur | 16/06/2018 | 22/06/2018 | Local coordinator |
| stc | Department of Chemistry | Challenges and opportunities in science and Technology | NIT-Hamirpur | 14/06/2010 | 18/06/2010 | Co-cordinator |
| stc | Department of Chemistry | Short Term Course Chemical and Biochemical and Environmental issues related to cancer and solutions addressing the problem | NIT-Hamirpur | 11/09/2017 | 16/09/2017 | Course coordinator |
| stc | Department of Chemical Engineering | Emerging electrical energy storage application | NIT-Hamirpur | 11/12/2017 | 16/12/2017 | Course coordinator |
| conference | Chemical Engineering Department | National Conference on Recent Trends in Chemical Sciences and Engineering RTCSE-2017 | NIT-Hamirpur | 13/10/2017 | 14/10/2017 | Co-Chairman |
| conference | Chemistry Department | National Conference on Analytical Chemistry and Molecular Spectroscopy | NIT-Hamirpur | 01/10/2016 | 01/10/2016 | Co-Chairman |
| conference | Chemistry Department | National Conference on Recent Trends in Chemical Sciences, Engineering and Technology (RTCET 2014) | NIT-Hamirpur | 29/05/2014 | 30/05/2014 | Co-convener |
| conference | Chemistry Department | Advances in polymer science and technology-APST-2010 | NIT-Hamirpur | 22/10/2010 | 24/10/2010 | Convener |
Expert Talks
| Title | Place | Year | Description of Event |
|---|
Consultancy
| Title of Consultancy | Client Organization | Faculty Involved | Amount(INR) | Status |
|---|---|---|---|---|
| Completed |
International and National Exposure
| Sr.No. | Title | Description |
|---|
Honors & Recognitions Achieved
| Sr.No. | Title | Activity | Given By | Year |
|---|---|---|---|---|
| 1 | Merit fellowship | Fifth position in Merit B.Sc(Hons.) | H.P. University | 1992 |
| 2 | Post-Doctoral fellowship | Research associate | CSIR-HRD | 2006 |